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5-Fluoro-3-pyridinecarbonyl chloride is a chemical compound with the molecular formula C6H3ClFNO. It is a derivative of pyridine, a heterocyclic aromatic compound, and features a fluorine atom at the 5-position, a carbonyl group at the 3-position, and a chloride group attached to the carbonyl carbon. 5-fluoro-3-pyridinecarbonyl chloride is often used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals due to its reactivity and the presence of the electron-withdrawing fluorine atom, which can influence the reactivity and properties of the final products. It is typically synthesized through the chlorination of 5-fluoro-3-pyridinecarboxylic acid or other related reactions. Handling of 5-fluoro-3-pyridinecarbonyl chloride requires appropriate safety measures due to its potential reactivity and toxicity.

350-04-9

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350-04-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 350-04-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,5 and 0 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 350-04:
(5*3)+(4*5)+(3*0)+(2*0)+(1*4)=39
39 % 10 = 9
So 350-04-9 is a valid CAS Registry Number.

350-04-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Fluoronicotinoyl chloride

1.2 Other means of identification

Product number -
Other names 5-fluoro-nicotinoyl chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:350-04-9 SDS

350-04-9Relevant academic research and scientific papers

Novel Inhibitors of an Insect Pest Chitinase: Design and Optimization of 9-O-Aromatic and Heterocyclic Esters of Berberine

Chen, Lei,Cheng, Jiagao,Qian, Xuhong,Shao, Xusheng,Yang, Qing,Zhu, Ling

, p. 7526 - 7533 (2021/07/26)

OfChi-h, a lepidopteran-exclusive glycoside hydrolase family 18 (GH18) chitinase from the agricultural insect pest Ostrinia furnacalis, is a promising molecular target candidate for pest control and management. Berberine (BER), a traditional Chinese medic

INDOLE AHR INHIBITORS AND USES THEREOF

-

Paragraph 0034-00346, (2018/11/22)

The present invention provides compounds useful as inhibitors of AHR, compositions thereof, and methods of using the same.

N-[5-(5-fluoropyridin-3-yl)-1H-pyrazol-3-yl]-4-piperidin-1-ylbutyramide (SEN78702, WYE-308775): A medicinal chemistry effort toward an α7 nicotinic acetylcholine receptor agonist preclinical candidate

Zanaletti, Riccardo,Bettinetti, Laura,Castaldo, Cristiana,Ceccarelli, Ilaria,Cocconcelli, Giuseppe,Comery, Thomas A.,Dunlop, John,Genesio, Eva,Ghiron, Chiara,Haydar, Simon N.,Jow, Flora,Maccari, Laura,Micco, Iolanda,Nencini, Arianna,Pratelli, Carmela,Scali, Carla,Turlizzi, Elisa,Valacchi, Michela

supporting information, p. 10277 - 10281 (2013/01/16)

α7 nicotinic acetylcholine receptors (α7 nAChR) represent promising therapeutic candidates for the treatment of cognitive impairment associated with Alzheimer's disease (AD) and schizophrenia. A medicinal chemistry effort around previously reported compound 1 (SEN15924, WAY-361789) led to the identification of 12 (SEN78702, WYE-308775) a potent and selective full agonist of the α7 nAChR that demonstrated improved plasma stability, brain levels, and efficacy in behavioral cognition models.

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