350036-98-5 Usage
Chemical Family
Belongs to the oxadiazole family, which is a group of heterocyclic compounds containing an oxadiazole ring.
Structure
Contains an oxadiazole ring with an attached amino group, making it a heterocyclic compound.
Potential Applications
Has potential applications in the field of pharmaceuticals due to its antibacterial and antifungal properties.
Intermediate in Synthesis
Known for its potential use as an intermediate in the synthesis of various organic molecules.
Versatility
Acts as a versatile building block in organic synthesis.
Industry Relevance
Valuable chemical in the pharmaceutical and agrochemical industries due to its diverse applications and properties.
CAS Registry Number
The compound is identified by the CAS Registry Number 71734-11-7.
Molecular Weight
The molecular weight of 1,2,4-Oxadiazol-3(2H)-one,5-amino-(9CI) is approximately 103.07 g/mol.
Solubility
The solubility of the compound may vary depending on the solvent used, but it is generally considered to be soluble in polar solvents like water and dimethyl sulfoxide (DMSO).
Stability
The compound is generally stable under normal conditions, but it should be stored away from heat, light, and moisture to maintain its stability and potency.
Safety Precautions
When handling 1,2,4-Oxadiazol-3(2H)-one,5-amino-(9CI), it is essential to follow proper safety protocols, including wearing gloves, protective eyewear, and a lab coat to minimize exposure to the compound.
Check Digit Verification of cas no
The CAS Registry Mumber 350036-98-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,0,0,3 and 6 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 350036-98:
(8*3)+(7*5)+(6*0)+(5*0)+(4*3)+(3*6)+(2*9)+(1*8)=115
115 % 10 = 5
So 350036-98-5 is a valid CAS Registry Number.
350036-98-5Relevant academic research and scientific papers
Synthesis method of 1, 2, 4-oxadiazole-3, 5-diketone
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Paragraph 0035-0039; 0041-0043; 0045-0047, (2021/08/19)
The invention relates to a synthesis method of 1, 2, 4-oxadiazole-3, 5-diketone. The method comprises the following steps: placing a reaction mixed solution of a compound 1 and an alkali solution in a reaction system, adding an oxidizing agent, reacting for a period of time, adjusting the pH to be acidic, performing filtering, and recrystallizing a filter cake to obtain a compound 2; and placing the compound 2, an inorganic solvent and an organic solvent in a reaction system, adding nitrite for a reaction, and after the reaction is finished, performing filtering and recrystallization to obtain the target compound 1, 2, 4-oxadiazole-3, 5-diketone. According to the method, the raw materials are few in variety and easy to obtain; reaction conditions are mild; compared with a synthesis method in the literature 2, the provided method has less three-waste emission and fewer steps; and hydroxylamine is used in the literature 2, and the requirement for equipment in industrial production is strict, while the hydroxylamine does not need to be used in the method, the process is simple, and the requirement for the equipment is low.
Synthetic and tautomeric studies of 5-amino-2,3-dihydro-1,2,4-oxadiazol-3-one
Ra, Do Young,Cho, Nam Sook,Kang, Sung Kwon,Choi, Eun Suk,Suh, Il Hwan
, p. 81 - 84 (2007/10/03)
5-Amino-2,3-dihydro-1,2,4-oxadiazol-3-one 2 was synthesized as an analogue of cytosine. Among the possible four tautomers it was established by spectroscopic methods and ab initio calculations that it exists as a lactam form 2b like cytosine. The NH is more acidic than NH2, thus it could be regioselectively mesylated and acetylated under basic conditions.
