350245-59-9Relevant academic research and scientific papers
Catalytic asymmetric synthesis of epoxides from aldehydes using sulfur ylides with in situ generation of diazocompounds
Aggarwal, Varinder K.,Alonso, Emma,Hynd, George,Lydon, Kevin M.,Palmer, Matthew J.,Porcelloni, Marina,Studley, John R.
, p. 1430 - 1433 (2001)
A practical, general, and convergent to epoxides with control of the relative and absolute stereochemistry has been achieved by generating the reactive intermediate (the diazo compound) in situ from tosylhydrazone salts (see scheme, PTC = phase-transfer catalyst, Ts = toluene-4-sulfonyl). High yields (58-82%), high d.r. (88:12-98:2), and high ee values (87-94%) have been obtained using a new class of stable chiral sulfides at low catalyst loading (5 mol%) and [Rh2(OAc)4] (0.5 mol%).
Highly regioselective rearrangement of 2-substituted vinylepoxides catalyzed by gallium(III) triflate
Deng, Xian-Ming,Sun, Xiu-Li,Tang, Yong
, p. 6537 - 6540 (2007/10/03)
Gallium(III) triflate catalyzed the rearrangement of 2-sub-stituted vinylepoxides into β,γ-unsaturated carbonyl compounds with high regio- and chemoselectivity (>97/3) in low catalyst loading (1-5 mol%). The alkyl-substituted trimethylsilylvinyl epoxides
