35047-51-9

Upstream product

• 61040-81-1 4-methyl-3,5-dimethoxybenzoic acid 
• 35052-27-8 3,5-dimethoxy-4-methylphenylmethyl alcohol 
• 60441-79-4 methyl 3,5-dimethoxy-4-methylbenzoate 

Downstream Products

• 187104-44-5 1,3-dimethoxy-2-methyl-5-[2-propenyl]-benzene 
• 717916-64-8 (S)-3-(3,5-Dimethoxy-4-methyl-phenyl)-2-methyl-propan-1-ol 
• 717916-65-9 (2S,3R,4S)-1-(3,5-Dimethoxy-4-methyl-phenyl)-2,4-dimethyl-hex-5-en-3-ol 
• 717916-66-0 (2R,3R,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(3,5-dimethoxy-4-methyl-phenyl)-2,4-dimethyl-pentanal 

Relevant academic research and scientific papers

Tandem Chloropalladation/Cyclization and Dearomative Cyclization toward Functionalized Tricyclic Bridged [3.2.1] Skeleton Compounds

A palladium-catalyzed tandem reaction is reported that involves chloropalladation/cyclization and dearomative cyclization to construct a tricyclic bridged [3.2.1] carbocyclic-skeleton and oxa- and aza-skeletons. In this domino process, a level of ring strain and other competitive reactions, i.e., protonolysis, β-hydride elimination, and chlorination of the C-Pd bond, were suppressed to the lowest level under mild reaction conditions.

NOVEL HETEROCYCLIC COMPOUNDS AS HSP90-INHIBITORS

Novel heterocyclic compounds are described and demonstrated to have utility as Heat Shock Protein 90 (HSP90) inhibiting agent. Method of synthesis and use of such compounds are also described.

Single step transformation of PMB ethers to bromides using a CBr4-TPP reagent system

PMB ethers are efficiently transformed to their corresponding bromides by a CBr4-TPP reagent system with a wide range of other functional groups also present in the substrate.

Synthesis of isochromans and their derivatives

Isochromans and their derivatives have been chemically synthesized. These compounds possess significant phytotoxic activity which may be used as a biodegradable contact herbicide. The synthetic method allows for economic production of these herbicides.

Syntheses of 3,7-Dimethyl-8-hydroxy-6-methoxyisochroman, the 3,7-Dimethyl-6-hydroxy-8-methoxy Isomer, and Their Ester and Ether Derivatives: Plant Growth Regulatory Activity

A systematic invesitgation of ester and ether derivatives of 3,7-dimethyl-8-hydroxy-6-methoxyisochroman and 3,7-dimethyl-6-hydroxy-8-methoxyisochroman has established that all of the derivatives synthesized exhibited activity in the wheat coleoptile assay, with several of the compounds being more active than the parent systems.