55483-01-7Relevant academic research and scientific papers
Synthesis of demethylated nidulol via an intramolecular Michael reaction
Jimenez, Rogelio,Maldonado, Luis A.,Salgado-Zamora, Hector
, p. 1274 - 1281 (2010)
An expeditious synthesis of 5,7-dihydroxy-6-methylphthalide from open-chain precursors is described. The key intermediates, synthons 3 and 4, were readily obtained from accessible materials and were further transformed to a common precursor, a five-membered lactone derivative, via an intramolecular Michael addition. Lactone 2 was aromatised to the phthalide system under basic conditions. The process thus constitutes a formal synthesis of the phthalide framework.
Hypoalectorialic acid and conechinocarpic acid, two new benzyl esters from lichens
Elix, John A.,Wardlaw, Judith H.
, p. 727 - 729 (2007/10/03)
The benzyl esters hypoalectorialic acid [6-(2′,4′-dihydroxy-3′,6′-dimethylbenzoyloxymethyl)-2,4- dihydroxy-3-methylbenzoic acid] (5) and conechinocarpic acid [1′,4′-dihydroxy-6′-methoxy-3′-oxo-1′,3′- dihydroisobenzofuran-5′-ylmethyl 2-hydroxy-4-methoxy-3,6-dimethylbenzoate] (7) have been isolated from the lichens Hypotrachyna hypoalectorialica and Relicina samoensis respectively. The structure of the compounds (5) and (7) followed from a combination of spectroscopic and chemical data.
Synthetic Confirmation of the Structure of the Lichen Benzyl Esters Alectorialic and Barbatolic Acids
Elix, John A.,Jayanthi, Vilas K.
, p. 1841 - 1850 (2007/10/02)
The total synthesis of methyl alectorialate (3) and methyl barbatolate (4) has been achieved, and the synthetic esters have been compared with naturally derived material.In addition alectorialin (decarboxylalectorialic acid) (5) and barbatolin (6) have be
