350620-58-5Relevant academic research and scientific papers
Double 1,4-addition of malonate to 1,2-diaza-1,3-butadienes: A useful route to previously unknown symmetric and unsymmetric 1,6-dioxo-2,7-diazaspiro [4.4] nona-3,8-dienes
Attanasi,De Crescentini,Filippone,Mantellini
, p. 534 - 537 (2001)
In the presence of sodium methoxide in tetrahydrofuran, 1,2-diaza-1,3-butadienes react with dimethyl malonate in a 2:1 molar ratio to give symmetric or unsymmetric bishydrazones that in turn produce new 1,6-dioxo-2,7-diazaspiro [4.4] nona-3,8-dienes, as a consequence of a double ring closure, on treatment with sodium methoxide in methanol.
