35081-00-6

Basic information

• Product Name: 5-(1,3-diphenyl-3-oxopropyl)pyrimidine-2,4,6(1H,3H,5H)-trione
• Synonyms: 5-(1,3-diphenyl-3-oxopropyl)pyrimidine-2,4,6(1H,3H,5H)-trione
• CAS NO: 35081-00-6
• Molecular Weight: 336.347
• Mol File: 35081-00-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-(1,3-diphenyl-3-oxopropyl)pyrimidine-2,4,6(1H,3H,5H)-trione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(1,3-diphenyl-3-oxopropyl)pyrimidine-2,4,6(1H,3H,5H)-trione(35081-00-6)
• EPA Substance Registry System: 5-(1,3-diphenyl-3-oxopropyl)pyrimidine-2,4,6(1H,3H,5H)-trione(35081-00-6)

Safety Data

• Hazardous Substances Data: 35081-00-6(Hazardous Substances Data)

Upstream product

• 873-83-6 4-Amino-2,6-dihydroxypyrimidine 
• 94-41-7 benzalacetophenone 
• 67-52-7 BARBITURIC ACID 
• 100-52-7 benzaldehyde 
• 98-86-2 acetophenone 
• 614-47-1 1,3-diphenyl-propen-3-one 

Relevant articles and documents

Pot, atom and step economic (PASE) synthesis of 5-monoalkylbarbiturates through domino aldol-Michael reaction

A simple pot, atom and step economic (PASE) approach for the synthesis of 5-monoalkylbarbiturates by a one-pot reaction of barbituric acids, aldehydes, and ketones, involving a domino aldol-Michael reaction is described. The operational simplicity and cost effectiveness of this procedure makes it a sustainable strategy for the synthesis of 5-monoalkylbarbiturates.

Synthesis of substituted and unsubstituted 5-(1,3-diaryl-1-oxopropyl) pyrimidine (1H, 3H, 5H)-2,4,6-triones

Reactions of 1,3-diaryl-2-propene-1-ones 2a-i give the corresponding 5-(1,3-diaryl-1-oxopropyl)pyrimidine-(1H,3H,5H)-2,4,6-triones 3a-i with barbituric acid 1 under refluxing condition without using any catalyst.