35099-60-6Relevant articles and documents
Rhodium-catalyzed C-C coupling reactions involving ring opening of strained molecules. II. Addition to olefins and aromatic substitution
Chiusoli, Gian Paolo,Costa, Mirco,Melli, Luca
, p. 495 - 506 (1988)
Rhodium-catalyzed C-C coupling reactions, involving ring opening of strained molecules, have been studied using diphenylmethylenecyclopropanes as models.It has been established that, as rhodium takes control of the ring opening process, activated olefins
Designing a Planar Chiral Rhodium Indenyl Catalyst for Regio- And Enantioselective Allylic C-H Amidation
Farr, Caitlin M. B.,Kazerouni, Amaan M.,Park, Bohyun,Poff, Christopher D.,Won, Joonghee,Sharp, Kimberly R.,Baik, Mu-Hyun,Blakey, Simon B.
supporting information, p. 13996 - 14004 (2020/09/18)
Chiral variants of group IX Cp and Cp? catalysts are well established and catalyze a broad range of reactions with high levels of enantioselectivity. Enantiocontrol in these systems results from ligand design that focuses on appropriate steric blocking. Herein we report the development of a new planar chiral indenyl rhodium complex for enantioselective C-H functionalization catalysis. The ligand design is based on establishing electronic asymmetry in the catalyst, to control enantioselectivity during the reactions. The complex is easily synthesized from commercially available starting materials and is capable of catalyzing the asymmetric allylic C-H amidation of unactivated olefins, delivering a wide range of high-value enantioenriched allylic amide products in good yields with excellent regio- and enantioselectivity. Computational studies suggest that C-H cleavage is rate- and enantio-determining, while reductive C-N coupling from the RhV-nitrenoid intermediate is regio-determining.
Extending the Substrate Scope in the Hydrogenation of Unfunctionalized Tetrasubstituted Olefins with Ir-P Stereogenic Aminophosphine-Oxazoline Catalysts
Biosca, Maria,Salomó, Ernest,De La Cruz-Sánchez, Pol,Riera, Antoni,Verdaguer, Xavier,Pàmies, Oscar,Diéguez, Montserrat
supporting information, p. 807 - 811 (2019/01/26)
Air-stable and readily available Ir-catalyst precursors modified with MaxPHOX-type ligands have been successfully applied in the challenging asymmetric hydrogenation of tetrasubstituted olefins under mild reaction conditions. Gratifyingly, these catalyst precursors are able to efficiently hydrogenate not only a range of indene derivatives (ee's up to 96%) but also 1,2-dihydronapthalene derivatives and acyclic olefins (ee's up to 99%), which both constitute the most challenging substrates for this transformation.
