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4-Nitro-N-(2,2,2-trifluoroethyl)aniline is an organic compound with the chemical formula C8H7F3N2O2. It is a derivative of aniline, featuring a nitro group at the 4-position and a trifluoroethyl group at the nitrogen atom. 4-nitro-N-(2,2,2-trifluoroethyl)aniline is characterized by its yellow crystalline appearance and is soluble in organic solvents. It is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals. Due to its reactivity and potential health hazards, it is important to handle 4-nitro-N-(2,2,2-trifluoroethyl)aniline with care, following proper safety protocols.

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  • 351-97-3 Structure
  • Basic information

    1. Product Name: 4-nitro-N-(2,2,2-trifluoroethyl)aniline
    2. Synonyms: 4-nitro-N-(2,2,2-trifluoroethyl)aniline
    3. CAS NO:351-97-3
    4. Molecular Formula:
    5. Molecular Weight: 220.151
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 351-97-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-nitro-N-(2,2,2-trifluoroethyl)aniline(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-nitro-N-(2,2,2-trifluoroethyl)aniline(351-97-3)
    11. EPA Substance Registry System: 4-nitro-N-(2,2,2-trifluoroethyl)aniline(351-97-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 351-97-3(Hazardous Substances Data)

351-97-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 351-97-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,5 and 1 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 351-97:
(5*3)+(4*5)+(3*1)+(2*9)+(1*7)=63
63 % 10 = 3
So 351-97-3 is a valid CAS Registry Number.

351-97-3Relevant articles and documents

Synthesis of tri(di)fluoroethylanilines via copper-catalyzed coupling reaction of tri(di)fluoroethylamine with (hetero)aromatic bromides

Chen, Suo,Wang, Hui,Jiang, Wei,Rui, Pei-Xin,Hu, Xiang-Guo

, p. 9799 - 9807 (2019)

We have realized the first Ullmann type coupling reaction of tri(di)fluoroethylamine with (hetero)aromatic bromides, employing 5-20 mol% Cu2O and an oxalamide ligand [N-(2,4,6-trimethoxyphenyl)acetamide]. This efficient and practical method has

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