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2,4,5,6-Tetrafluoronicotinic acid is a synthetic organic compound characterized by its molecular formula C6HF4NO2. It is a derivative of nicotinic acid (vitamin B3), where four hydrogen atoms have been replaced by fluorine atoms. 2,4,5,6-Tetrafluoronicotinic acid is known for its potential applications in the synthesis of various pharmaceuticals and agrochemicals due to its unique electronic properties that can influence the activity of the final products. The tetrafluorination of the nicotinic acid structure can enhance the lipophilicity and metabolic stability of the molecules in which it is incorporated, making it a valuable building block in medicinal chemistry.

3512-15-0

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3512-15-0 Usage

Derivative of

Nicotinic acid

Characterized by

Four fluorine atoms on the aromatic ring

Physical state at room temperature

White solid

Solubility

Soluble in water

Uses

Building block in the synthesis of pharmaceuticals and agrochemicals, ligand in coordination chemistry, precursor for other fluorinated compounds

Value

Unique chemical properties and structural features for the development of new materials and compounds in the chemical and pharmaceutical industries.

Check Digit Verification of cas no

The CAS Registry Mumber 3512-15-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,5,1 and 2 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 3512-15:
(6*3)+(5*5)+(4*1)+(3*2)+(2*1)+(1*5)=60
60 % 10 = 0
So 3512-15-0 is a valid CAS Registry Number.

3512-15-0Relevant academic research and scientific papers

Preparation and reactions of 2,3,4,6-tetrafluoropyridine and its derivatives

Coe, Paul L.,Rees, Anthony J.

, p. 45 - 60 (2007/10/03)

A reliable route to 2,3,4,6-tetrafluoropyridine has been established starting from the readily available 3,5-dichlorotrifluoropyridine by halogen exchange under controlled conditions to give 3-chlorotetrafluoropyridine and its subsequent hydrodechlorination using hydrogen over palladium on alumina at 250-270°C. The formation and reactions of the 3-lithio derivative have been studied with the aim of obtaining 3,4-disubstituted trifluoropyridines. Routes to such materials have been developed and their conversion to deazapurine derivatives as potential substrates for the generation of anti-sense nucleosides are reported.

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