35129-66-9

Upstream product

• 920-39-8 isopropylmagnesium bromide 
• 100-47-0 benzonitrile 
• 110-89-4 piperidine 
• 72846-70-9 isopropyl phenyl ketoxime 
• 75-26-3 isopropyl bromide 
• 1068-55-9 isopropylmagnesium chloride 
• 1888-75-1 isopropyllithium 
• 611-69-8 rac-2-methyl-1-phenylpropan-1-ol 

Downstream Products

• 51110-17-9 2-methyl-1-phenyl-1-propenyl isothiocyanate 
• 97704-60-4 N-(2-Methyl-1-phenyl-propenyl)-acetimidic acid methyl ester 
• 133682-27-6 1-isopropoxy-4-methyl-3-phenyl-2-aza-1,3-pentadiene 
• 141070-90-8 N-(2-Methyl-1-phenyl-propenyl)-formimidic acid propyl ester 
• 106722-55-8 N-(2-Methyl-1-phenyl-propenyl)-formimidic acid ethyl ester 
• 133682-46-9 4,4-dimethyl-1,3-diphenyl-2-aza-1,3-butadiene 
• 133682-45-8 4,4-dimethyl-1-dimethylamino-3-phenyl-2-aza-1,3-butadiene 
• 115611-71-7 1-ethoxy-1,4,4-trimethyl-3-phenyl-2-aza-1,3-butadiene 
• 139006-94-3 N-ethoxycarbonylmethyl-N-(2-methyl-1-phenyl)propylideneamine 
• 141071-08-1 N-formyl-2-methyl-1-phenyl-1-propenylamine 
• 115611-72-8 N-(2-Methyl-1-phenyl-propenyl)-propionimidic acid ethyl ester 
• 28153-43-7 1-Phenyl-2-methyl-propenylisocyanat 
• 13248-11-8 2-<1-Phenyl-isobutyliden>-indan-1,3-dion 
• 139006-97-6 2-[2-Methyl-1-phenyl-prop-(E)-ylideneamino]-butyric acid ethyl ester 

Relevant academic research and scientific papers

Urea-Oxaziridines

Chemoselective conjugation is achieved through redox reactivity by reacting an N-transfer oxidant with a thioether substrate in a redox reaction in an aqueous environment to form a conjugation product. In embodiments, Redox-Activated Chemical Tagging (ReACT) strategies for methionine-based protein functionalization. Oxaziridine (Ox) compounds serve as oxidant-mediated reagents for direct functionalization by converting methionine to the corresponding sulfimide conjugation product.

CATALYTIC PREPARATION OF ENAMIDES FROM ALKYL AZIDES AND ACYL DONORS

The present invention relates to a method to synthesize an enamide compound by generating imine which does not have a substituent group bonded to the nitrogen from an organic azide compound and conducting a reaction of the same with acyl doner. By using t

Exploiting the Nucleophilicity of N-H Imines: Synthesis of Enamides from Alkyl Azides and Acid Anhydrides

The nucleophilicity of N-unsubstituted imines, which were generated from alkyl azides by a ruthenium-catalyzed reaction, was investigated in the reaction with acid anhydrides. The initial products were N-acylimines, which isomerized to the corresponding e

Manganese-catalyzed dehydrogenative [4+2] annulation of N-H imines and alkynes by C-H/N-H activation

Described herein is a manganese-catalyzed dehydrogenative [4+2] annulation of N-H imines and alkynes, a reaction providing highly atom-economical access to diverse isoquinolines. This transformation represents the first example of manganese-catalyzed C-H activation of imines; the stoichiometric variant of the cyclomanganation was reported in 1971. The redox neutral reaction produces H2 as the major byproduct and eliminates the need for any oxidants, external ligands, or additives, thus standing out from known isoquinoline synthesis by transition-metal-catalyzed C-H activation. Mechanistic studies revealed the five-membered manganacycle and manganese hydride species as key reaction intermediates in the catalytic cycle.

New stable N-H oxaziridines - Synthesis and reactivity

A number of stable new N-H oxaziridines have been designed and prepared, and their reactivity as electrophilic sources of nitrogen investigated. 3-tert-Butyl-3-phenyloxaz-ridine is the most efficient and stable and has potential for use as a general reagent for this purpose.

A convenient synthesis of tertiary carbinamines via N-aluminum ketimines

Reaction of N-unsubstituted ketimines with organoaluminum reagents prepared from allylic and propargylic halides, allows to prepare, in good yields, tertiary carbinamines with three different groups (phenyl, alkyl and α-unsaturated group) on die tertiary carbon center.

Ruthenium Complex Catalyzed Selective Deoxygenation of Ketoximes to Ketimines

Ru3(CO)12 showed high catalytic activity for the deoxygenation of various ketoximes to the corresponding ketimines under carbon monoxide pressure (20 kg/cm2).For the deoxygenation of propiophenone oxime, ethyl phenyl ketimine was obtained in 100 percent yield.On the other hand, heptanal oxime which was aldoxime was dehydrated under the same conditions to the corresponding nitrile in 32 percent yield.

N-Acyl- and N-Aryl-N'-alkylidenureas as Precursors of Isocyanates or Acylisocyanates

Derivatives of isocyanates or acylisocyanates were prepared by reactions with ketimines.Fragmentation reactions of the product were examined.