3513-39-1

Usage

Type

Chemical compound

Field of use

Organic chemistry

Structure

Bicyclic compound containing a ketone functional group

Derivative of

1H-inden-1-one

Functional groups

Nitrophenyl group, phenyl group

Usage

Building block in the synthesis of complex organic molecules, development of new drugs and pharmaceuticals, potential applications in materials science and industrial processes

Unique features

Chemical structure and properties

Upstream product

• 1942-30-9 4-(phenylethynyl)nitrobenzene 
• 5159-41-1 2-iodobenzyl alcohol 
• 6630-33-7 ortho-bromobenzaldehyde 
• 1801-42-9 2,3-diphenyl-1H-inden-1-one 
• 94873-25-3 3-hydroxy-2-nitro-2-(4-nitro-phenyl)-3-phenyl-indan-1-one 

Downstream Products

• 24016-99-7 2,3-Dinitro-3-phenyl-2-<4-nitro-phenyl>-hydrinden-1-on 
• 13304-39-7 2-(4-amino-phenyl)-3-phenyl-inden-1-one 

Relevant academic research and scientific papers

Palladium-catalyzed annulation of alkynes with ortho -halide-containing benzyl alcohols in aqueous medium

The Pd-catalyzed annulations of ortho-halide-containing benzyl alcohols with alkynes for the synthesis of indenones were achieved in aqueous Triton X-100 micelles with good yields and wide substrate scopes. Moreover, the indenones obtained in this procedure can be further functionalized to form some more synthetic useful derivatives via an environmental-friendly way.

Facile synthesis of indenones by cyclopalladated ferrocenylimine-catalyzed annulation of internal alkynes

An efficient and facile protocol for the annulation of o-halobenzaldehyde derivatives with diverse internal alkynes has been developed using cyclopalladated ferrocenylimine as the catalyst, and the indenones as the products could be obtained in moderate t