351379-10-7

Upstream product

• 50-00-0 formaldehyd 
• 351378-62-6 5-iodo-2-methoxy-3-methyl-phenol 
• 351378-60-4 2-hydroxy-5-iodo-3-methylphenyl 4-methylbenzenesulfonate 
• 244126-22-5 toluene-4-sulfonic acid 2-hydroxy-3-methyl-phenyl ester 
• 488-17-5 3-methylbenzene-1,2-diol 
• 351380-16-0 toluene-4-sulfonic acid 5-iodo-2-methoxy-3-methyl-phenyl ester 

Downstream Products

• 351378-64-8 (2-benzyloxy-6-iodo-3-methoxy-4-methyl-phenyl)-methanol 
• 851121-88-5 {2-(5-allyloxy-1-benzyloxymethyl-4-hydroxy-7,8-dimethoxy-6-methyl-3,4-dihydro-1H-isoquinolin-2-yl)-1-[3-benzyloxy-4-methoxy-2-(4-methoxy-benzyloxymethyl)-5-methyl-benzyl]-2-oxo-ethyl}-methyl-carbamic acid tert-butyl ester 
• 851122-04-8 [2-(5-allyloxy-1-benzyloxymethyl-4-hydroxy-7,8-dimethoxy-6-methyl-3,4-dihydro-1H-isoquinolin-2-yl)-1-(3-benzyloxy-2-hydroxymethyl-4-methoxy-5-methyl-benzyl)-2-oxo-ethyl]-methyl-carbamic acid tert-butyl ester 
• 851121-89-6 [2-(5-allyloxy-1-benzyloxymethyl-7,8-dimethoxy-6-methyl-4-oxo-3,4-dihydro-1H-isoquinolin-2-yl)-1-(3-benzyloxy-2-formyl-4-methoxy-5-methyl-benzyl)-2-oxo-ethyl]-methyl-carbamic acid tert-butyl ester 
• 851122-06-0 C₄₆H₅₆N₂O₇Si 
• 851121-90-9 C₄₃H₄₆N₂O₈ 
• 851121-96-5 C₃₉H₄₈N₂O₉Si 
• 851122-08-2 C₃₉H₄₆N₂O₉Si 
• 851122-07-1 C₃₉H₄₈N₂O₈Si 
• 851122-05-9 C₄₀H₄₄N₂O₈ 
• 851121-91-0 C₄₀H₄₂N₂O₇ 
• 851121-95-4 C₃₉H₅₀N₂O₇Si 
• 851121-93-2 C₃₂H₃₀N₂O₉ 
• 851121-92-1 C₃₂H₃₀N₂O₈ 

Relevant academic research and scientific papers

Total synthesis of cribrostatin IV: Fine-tuning the character of an amide bond by remote control

We report the enantioselective total synthesis of cribrostatin IV (1). Key features of this synthesis involve the convergent coupling of two highly functionalized homochiral components followed by a "lynchpin" Mannich cyclization to establish the pentacyc