351424-33-4Relevant academic research and scientific papers
Inhibition of carbonic anhydrase isoforms I, II, IV, VII and XII with carboxylates and sulfonamides incorporating phthalimide/phthalic anhydride scaffolds
El-Azab, Adel S.,Abdel-Aziz, Alaa A.-M.,Ayyad, Rezk R.,Ceruso, Mariangela,Supuran, Claudiu T.
, p. 20 - 25 (2015/12/23)
We report a panel of carboxylates and sulfonamides incorporating phthalic anhydride and phthalimide moieties in their structure and their interaction with the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1). They were synthesized from substituted anthra
