351439-95-7Relevant academic research and scientific papers
Synthesis of 1,4-imino-L-lyxitols modified at C-5 and their evaluation as inhibitors of GH38 α-mannosidases
Bella, Maro?,?esták, Sergej,Monco?, Ján,Koó?, Miroslav,Poláková, Monika
supporting information, p. 2156 - 2162 (2018/09/04)
A synthetic approach to 1,4-imino-L-lyxitols with various modifications at the C-5 position is reported. These imino-L-lyxitol cores were used for the preparation of a series of N-(4-halobenzyl)polyhydroxypyrrolidines. An impact of the C-5 modification on
Regio- and stereoselective ring opening of epoxides. Enantioselective synthesis of 2,3,4-trisubstituted five-membered heterocycles
Diez, David,Beneitez,Marcos, Isidro S.,Garrido,Basabe,Urones, Julio G.
, p. 639 - 646 (2007/10/03)
By using the appropriate protecting groups, the opening of (2S,3S,4E)-5-benzenesulfonyl-2,3-epoxy-pent-4-en-1-ol (-)-2 could be controlled and used for the synthesis of the enantiomeric pyrrolidines (+)- and (-)-18 and the tetrahydrofuran analogs (+)- and (-)-19.
Enantioselective synthesis of a 2,3,4-trisubstituted pyrrolidine from 1-hydroxymethyl-4-phenylsulfonylbutadiene
Díez, David,Beneitez, M. Templo,Marcos, Isidro S.,Garrido,Basabe,Urones, Julio G.
, p. 655 - 657 (2007/10/03)
A chiral 2,3,4-trisubstituted pyrrolidine glycosidase inhibitor has been obtained from 1-hydroxymethyl-4-sulfonylbutadiene.
Preparation and biological evaluation of pyrrolidinediols and pyrrolidine N-oxides from D-ribose using the nitrone approach
Palmer, Andreas M.,Jaeger, Volker
, p. 2547 - 2558 (2007/10/03)
The transformation of 3,4-isopropylidenedioxy-5-methylpyrrolidine 1-oxides with various 2-substituents into the free diols and, by reduction, into the corresponding pyrrolidinediols (iminoglycitols) is described. The pyrrolidine N-oxides were derived from
