177569-80-1

Upstream product

• 50600-40-3 (3aS,4S,6aR)-4-(iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole 
• 532-20-7 D-Ribose 
• 100-46-9 benzylamine 
• 4099-85-8 methyl 2,3-O-isopropylidene-D-ribofuranoside 
• 155934-55-7 (4R,5R)-2,2-dimethyl-5-vinyl-[1,3]dioxolane-4-carbaldehyde 
• 177493-30-0 5-O-(tert-butyldimethylsilyl)-1,4-bis(methanesulfonyl)-2,3-di-O-isopropylidene-D-ribitol 
• 177493-29-7 5-O-(tert-butyldimethylsilyl)2,3-di-O-isopropylidene-D-ribitol 
• 217309-46-1 5-(tert-butyldimethylsilyloxy)-2,3-isopropylidenedioxy-D-ribofuranose 
• 177493-31-1 (2S,3R,4S)-<1-Benzyl-3,4-(isopropylidenedioxy)pyrrolidin-2-yl>methyl methanesulfonate 
• 177569-79-8 (3aR,4S,6aS)-5-benzyl-4-((tert-butyldimethylsilyloxy)methyl)-2,2-dimethyltetrahydro-3aH-[1,3]dioxolo[4,5-c]pyrrole 

Downstream Products

• 144848-73-7 (3R,4S,5S)-1-Benzyl-3-fluoro-4,5-(isopropylidenedioxy)piperidine 
• 144848-72-6 (3R,4R,5S)-1-Benzyl-4,5-(isopropylidenedioxy)piperidin-3-ol 
• 177767-33-8 <(3R)-(3α,4α,5α)>-1-Benzylpiperidine-3,4,5-triol 
• 177493-27-5 (3S,4S,5R)-1-Benzyl-5-fluoropiperidin-3,4-diol 
• 177493-26-4 (3S,4R,5R)-5-Azido-1-benzylpiperidine-3,4-diol 
• 176218-82-9 (2S,3R,4S)-2-azidomethyl-1-benzyl-3,4-(O-isopropylidene)dihydroxypyrrolidine 
• 177493-32-2 (3R,4R,5S)-3-Azido-1-benzyl-4,5-(isopropylidenedioxy)piperidine 
• 186204-80-8 (3aS,7R,7aR)-5-benzyl-2,2,7-trimethylhexahydro-[1,3]dioxolo[4,5-c]pyridine 

Relevant academic research and scientific papers

Synthesis of 1,4-imino-L-lyxitols modified at C-5 and their evaluation as inhibitors of GH38 α-mannosidases

A synthetic approach to 1,4-imino-L-lyxitols with various modifications at the C-5 position is reported. These imino-L-lyxitol cores were used for the preparation of a series of N-(4-halobenzyl)polyhydroxypyrrolidines. An impact of the C-5 modification on

Synthesis of N-alkyl substituted iminosugars from D-ribose

An effective and facile method for the synthesis of N-alkylated hydroxylpyrrolidine and hydroxylpiperidine is described. A number of N-alkyl substituted iminosugars were prepared using iodine-induced intramolecular cyclization of acyclic alkenylamines as key step.

Preparation of optically active 3-substituted piperidines via ring expansion: Synthesis of 4-amino- and 4-fluoro-1,4,5-trideoxy-1,5-imino-D-ribitol and 1,5-dideoxy-1,5-imino-D-ribitol

A new method for the preparation of optically active 3-substituted 1-benzylpiperidines based on the ring expansion of the 1-benzyl-2-(methylsulfonyloxymethyl)pyrrolidine 13 with various nucleophiles has been described. Synthesis of 4-amino-1,4,5-trideoxy-1,5-imino-D-ribitol 5, 1,4,5-trideoxy-4-fluoro-1,5-imino-D-ribitol 6 and 1,5-dideoxy-1,5-imino-D-ribitol 7 has also been achieved by a route which involves ring expansion of compound 13.