35190-17-1

Basic information

• Product Name: 3,3'-Dichlorobenzoin
• Synonyms: 1,2-Bis(3-chlorophenyl)-2-hydroxyethanone;3,3'-Dichlorobenzoin
• CAS NO: 35190-17-1
• Molecular Formula: C₁₄H₁₀Cl₂O₂
• Molecular Weight: 281.13
• Mol File: 35190-17-1.mol
• Article Data: 23

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,3'-Dichlorobenzoin(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3'-Dichlorobenzoin(35190-17-1)
• EPA Substance Registry System: 3,3'-Dichlorobenzoin(35190-17-1)

Safety Data

• Hazardous Substances Data: 35190-17-1(Hazardous Substances Data)

Upstream product

• 37580-83-9 1,2-bis(3-chlorophenyl)-1,2-ethanediol 
• 587-04-2 m-Chlorobenzaldehyde 
• 78-84-2 isobutyraldehyde 
• 2043-61-0 cyclohexanecarbaldehyde 
• 104-53-0 3-phenyl-propionaldehyde 
• 292638-85-8 acrylic acid methyl ester 
• 92133-96-5 (1H-benzo[d][1,2,3]triazol-1-yl)(3-chlorophenyl)methanone 
• 64-17-5 ethanol 

Downstream Products

• 5216-30-8 1,2-bis(3-chlorophenyl)ethyne 
• 261356-82-5 ethyl 4-(3-chlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 37580-83-9 1,2-bis(3-chlorophenyl)-1,2-ethanediol 
• 119488-20-9 1,2-bis-(3-chloro-phenyl)-ethanone 
• 1591704-25-4 (S)-1,2-bis(3-chlorophenyl)-2-oxoethyl butyrate 
• 1426437-54-8 2,3-bis(3-chlorophenyl)-6-methylquinoxaline 
• 1414943-90-0 4,5-bis(3-chlorophenyl)-2-(4-methoxyphenyl)-1H-imidazole 
• 1414943-86-4 4,5-bis(3-chlorophenyl)-2-phenyl-1H-imidazole 
• 7408-32-4 2,3-bis(3-chlorophenyl)quinoxaline 
• 1338828-74-2 C₂₁H₁₅Cl₂NO 
• 1293372-31-2 4,5-bis-(3-chlorophenyl)-5H-[1,2,3]oxathiazole 2,2-dioxide 
• 1293372-45-8 (4S,5R)-4,5-bis-(3-chlorophenyl)-[1,2,3]oxathiazolidine 2,2-dioxide 

Relevant articles and documents

Isostructurality of quinoxaline crystal phases: The interplay of weak hydrogen bonds and halogen bonding

Tailoring the physical properties of molecular crystals though the construction of solid solutions requires the existence of isostructural crystals. Simple substitutions of a given molecular framework can give a range of different crystal structures. A se

The Direct Conversion of α-Hydroxyketones to Alkynes

Alkynes are highly important functional groups in organic chemistry, both as part of target structures and as versatile synthetic intermediates. In this study, a protocol for the direct conversion of α-hydroxyketones to alkynes is reported. In combination with the variety of synthetic methods that generate the required starting materials by forming the central C-C bond, it enables a highly versatile fragment coupling approach toward alkynes. A broad scope for this novel transformation is shown alongside mechanistic insights. Furthermore, the utility of our protocol is demonstrated through its application in concert with varied α-hydroxyketone syntheses, giving access to a broad spectrum of alkynes.

Palladium-Catalyzed Chemo- and Enantioselective C?O Bond Cleavage of α-Acyloxy Ketones by Hydrogenolysis

A chemoselective C?O bond cleavage of the ester alkyl side-chain of α-acyloxy ketones was realized for the first time by a highly efficient palladium-catalyzed hydrogenolysis (S/C=6000, the highest catalytic efficiency by far). Furthermore, a kinetic resolution of α-acyloxy ketones was first developed by enantioselective hydrogenolysis with good yields and up to 99 % ee.