119488-20-9Relevant articles and documents
Palladium-Catalyzed Chemo- and Enantioselective C?O Bond Cleavage of α-Acyloxy Ketones by Hydrogenolysis
Chen, Jianzhong,Zhang, Zhenfeng,Liu, Delong,Zhang, Wanbin
, p. 8444 - 8447 (2016/07/19)
A chemoselective C?O bond cleavage of the ester alkyl side-chain of α-acyloxy ketones was realized for the first time by a highly efficient palladium-catalyzed hydrogenolysis (S/C=6000, the highest catalytic efficiency by far). Furthermore, a kinetic resolution of α-acyloxy ketones was first developed by enantioselective hydrogenolysis with good yields and up to 99 % ee.
ENCOUNTER OF AN INFERIOR INTRAMOLECULAR CYCLIZATION IN AN APPROACH TOWARD THE SYNTHESIS OF 10-OXO-2-THIAMETACYCLOPHANE:PREPARATION OF TWO ISOMERIC DIOXO-2,19-DITHIAMETACYCLOPHANES
Lai, Yee-Hing,Yeo, Lay-Hoon
, p. 1629 - 1636 (2007/10/02)
The sodium sulfide coupling of 1,2-bis(3-bromomethyl)phenylethanone, prepared in seven steps from m,α-dichlorotoluene, was attempted but failed to yield the desired 10-oxo-2-thia-metacyclophane.This is attributed to unfavorable geometry in the thiacy