35190-71-7

Usage

Uses

Used in Organic Synthesis:
(2-([2-(Hydroxymethyl)phenyl]disulfanyl)phenyl)methanol is used as a building block in organic synthesis for the formation of disulfide bonds in proteins and peptides. Its unique structure allows for the creation of complex molecules that are important in the study of biological and pharmaceutical compounds.
Used in Biological and Pharmaceutical Research:
In the field of biological and pharmaceutical research, (2-([2-(Hydroxymethyl)phenyl]disulfanyl)phenyl)methanol is used as a key component in the development of new drugs and therapies. Its ability to form disulfide bonds makes it a valuable tool in the study of protein structure and function, as well as in the design of novel therapeutic agents.
Used in Materials Science:
(2-([2-(Hydroxymethyl)phenyl]disulfanyl)phenyl)methanol has been studied for its potential applications in materials science. Its unique structure and properties make it a promising candidate for the development of new materials with specific characteristics, such as improved stability or reactivity.
Used in Catalysis:
In the field of catalysis, (2-([2-(Hydroxymethyl)phenyl]disulfanyl)phenyl)methanol has been investigated for its potential use as a catalyst or catalyst precursor. Its ability to form disulfide bonds and its reactivity make it a candidate for facilitating various chemical reactions, potentially leading to more efficient and environmentally friendly processes.

Upstream product

• 147-93-3 Thiosalicylic acid 
• 922-67-8 propynoic acid methyl ester 
• 100790-03-2 n-butyl 2-(hydroxymethyl)phenyl sulfoxide 
• 4521-31-7 o-hydroxymethyl thiophenol 
• 119-80-2 2,2'-dithiobenzoic acid 
• 4892-02-8 Methyl thiosalicylate 

Downstream Products

• 412304-64-4 2-chloro-6-hydroxymethyl-benzenesulfonyl chloride 
• 1075725-78-8 2-(4-benzylpiperazin-1-yl)-N'-(2-mercaptobenzylidene)acetohydrazide 
• 1075725-80-2 N',N''-(2,2'-disulfanediylbis(2,1-phenylene)bis(methan-1-yl-1ylidene))bis(2-(4-benzylpiperazin-1-yl)acetohydrazide) 
• 79467-22-4 (2-((2-(aminomethyl)phenyl)thio)phenyl)methanol 
• 203512-55-4 2-((2-(hydroxymethyl)phenyl)thio)benzonitrile 
• 1069086-95-8 3-({[2-(hydroxymethyl)phenyl]sulfanyl}methyl)bicyclo[2.2.1]heptan-2-one 
• 29199-11-9 2-formylthiophenol 
• 55164-16-4 2,2'-dithiodibenzaldehyde 
• 4521-31-7 o-hydroxymethyl thiophenol 
• 81890-67-7 bis-(2-bromomethyl-phenyl)-disulfide 
• 4521-39-5 bis-(2-chloromethyl-phenyl)-disulfide 

Relevant academic research and scientific papers

Sequential C-H activation enabled expedient delivery of polyfunctional arenes

Modular construction of polyfunctional arenes from abundant feedstocks stands as an unremitting pursue in synthetic chemistry, accelerating the discovery of drugs and materials. Herein, using the multiple C-H activation strategy with versatile imidate esters, the expedient delivery of molecular libraries of densely functionalized sulfur-containing arenes was achieved, which enabled the concise construction of biologically active molecules, such as Bipenamol.

Aerobic oxidation of thiols to disulfides under ball-milling in the absence of any catalyst, solvent, or base

An efficient aerobic chemoselective oxidation of thiols to disulfides has been achieved under ball-milling over neutral aluminium oxide (grinding auxiliary) in the absence of any catalyst, co-oxidant, solvent, or base. A wide variety of functionalized diaryl, diheteroaryl and dialkyl disulfides have been obtained in high yields. The Royal Society of Chemistry 2013.

Development of a tandem base-catalyzed, triphenylphosphine-mediated disulfide reduction-Michael addition

A tandem disulfide reduction-Michael addition was developed using both free and polymer-bound triphenylphosphine as the reducing agent. The procedure was applied to intermolecular systems for the synthesis of arylsulfanyl- and alkylsulfanyl-substi-tuted p

COMPOSITIONS AND METHODS INCLUDING CELL DEATH INDUCERS AND PROCASPASE ACTIVATION

Compositions and methods are disclosed in embodiments relating to induction of cell death such as in cancer cells. Compounds and related methods for synthesis and use thereof, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells are disclosed. Compounds are disclosed in connection with modification of procaspases such as procaspase-3. In embodiments, compositions are capable of activation of procaspase-3.

Asymmetric copper complexes of stable mono-tert-butyl monobenzyl dithioether N2S2 ligands

Attempts to form copper complexes of new N2S2 compounds, in which one sulfur donor is a thiolate and the other a thioether, have been made by protecting the potential thiolate through tert-butylation and benzylating the other. Wherea

Chemistry of Sulfenic Acids. 7. Reason for the High Reactivity of Sulfenic Acids. Stabilization by Intramolecular Hydrogen Bonding and Electronegativity Effects

It is proposed that the reason sulfenic acids (RSOH) are so reactive and usually not isolated or even detected is that they form thiosulfinates (RS(O)SR) so readily.This is a consequence of the sulfenic acid hydrogen-bonded dimer, 1, which lowers the energy of activation for thiosulfinate formation.The stability of the few sulfenic acids that have been isolated can be explained in terms of steric, electronic, and intramolecular hydrogen-bonding effects which prevent dimer formation.The importance of these effects on the stability of simple unstable sulfenic acids was demonstrated by flash vacuum pyrolysis (FVP) and the thiosulfinate/vinyl sulfoxide ratio.A novel, high yield, rearrangement of sulfenic acid 19f to 1,3-benzothiazine 26 was observed.