35190-71-7

Basic information

• Product Name: (2-([2-(HYDROXYMETHYL)PHENYL]DISULFANYL)PHENYL)METHANOL
• Synonyms: (2-([2-(HYDROXYMETHYL)PHENYL]DISULFANYL)PHENYL)METHANOL;2,2'-DITHIODIBENZENEMETHANOL;BIS[2-(HYDROXYMETHYL)PHENYL] DISULFIDE;Benzenemethanol, 2,2'-dithiobis-
• CAS NO: 35190-71-7
• Molecular Formula: C₁₄H₁₄O₂S₂
• Molecular Weight: 278.39
• Mol File: 35190-71-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 451.1 °C at 760 mmHg
• Flash Point: 218.9 °C
• Appearance: /
• Density: 1.35 g/cm³
• CAS DataBase Reference: (2-([2-(HYDROXYMETHYL)PHENYL]DISULFANYL)PHENYL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (2-([2-(HYDROXYMETHYL)PHENYL]DISULFANYL)PHENYL)METHANOL(35190-71-7)
• EPA Substance Registry System: (2-([2-(HYDROXYMETHYL)PHENYL]DISULFANYL)PHENYL)METHANOL(35190-71-7)

Safety Data

• Hazardous Substances Data: 35190-71-7(Hazardous Substances Data)

Usage

General Description

(2-([2-(hydroxymethyl)phenyl]disulfanyl)phenyl)methanol is a chemical compound with the molecular formula C14H14O2S2. It is a white solid that is used in organic synthesis. (2-([2-(HYDROXYMETHYL)PHENYL]DISULFANYL)PHENYL)METHANOL is composed of a central methanol group attached to two phenyl rings, each of which contains a disulfanyl group and a hydroxymethyl group. It is commonly used in the formation of disulfide bonds in proteins and peptides, making it an important building block in the study of biological and pharmaceutical molecules. Additionally, it has been studied for its potential applications in materials science and catalysis.

Upstream product

• 922-67-8 propynoic acid methyl ester 
• 100790-03-2 n-butyl 2-(hydroxymethyl)phenyl sulfoxide 
• 4892-02-8 Methyl thiosalicylate 
• 119-80-2 2,2'-dithiobenzoic acid 
• 4521-31-7 o-hydroxymethyl thiophenol 
• 147-93-3 Thiosalicylic acid 

Downstream Products

• 55164-16-4 2,2'-dithiodibenzaldehyde 
• 79467-22-4 (2-((2-(aminomethyl)phenyl)thio)phenyl)methanol 
• 203512-55-4 2-((2-(hydroxymethyl)phenyl)thio)benzonitrile 
• 1075725-78-8 2-(4-benzylpiperazin-1-yl)-N'-(2-mercaptobenzylidene)acetohydrazide 
• 1075725-80-2 N',N''-(2,2'-disulfanediylbis(2,1-phenylene)bis(methan-1-yl-1ylidene))bis(2-(4-benzylpiperazin-1-yl)acetohydrazide) 
• 1069086-95-8 3-({[2-(hydroxymethyl)phenyl]sulfanyl}methyl)bicyclo[2.2.1]heptan-2-one 
• 412304-64-4 2-chloro-6-hydroxymethyl-benzenesulfonyl chloride 
• 4521-31-7 o-hydroxymethyl thiophenol 
• 81890-67-7 bis-(2-bromomethyl-phenyl)-disulfide 
• 4521-39-5 bis-(2-chloromethyl-phenyl)-disulfide 
• 29199-11-9 2-formylthiophenol 

Relevant articles and documents

Sequential C-H activation enabled expedient delivery of polyfunctional arenes

Modular construction of polyfunctional arenes from abundant feedstocks stands as an unremitting pursue in synthetic chemistry, accelerating the discovery of drugs and materials. Herein, using the multiple C-H activation strategy with versatile imidate esters, the expedient delivery of molecular libraries of densely functionalized sulfur-containing arenes was achieved, which enabled the concise construction of biologically active molecules, such as Bipenamol.

Development of a tandem base-catalyzed, triphenylphosphine-mediated disulfide reduction-Michael addition

A tandem disulfide reduction-Michael addition was developed using both free and polymer-bound triphenylphosphine as the reducing agent. The procedure was applied to intermolecular systems for the synthesis of arylsulfanyl- and alkylsulfanyl-substi-tuted p

A convenient reduction of highly functionalized aromatic carboxylic acids to alcohols with borane-THF and boron trifluoride-etherate

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