351902-64-2Relevant academic research and scientific papers
New C2-symmetrical 1,2-diphosphanes for the efficient rhodium-catalyzed asymmetric hydroboration of styrene derivatives
Demay, Steandphane,Volant, Florence,Knochel, Paul
, p. 1235 - 1238 (2007/10/03)
A double [2,3] sigmatropic rearrangement enables the fast synthesis of novel C2-symmetrical 1,2-diphosphanes in good yields. These phosphanes (for example, 1; c-Hex = cyclohexyl) are highly efficient ligands for the rhodium-catalyzed asymmetric hydroboration of a wide variety of styrenes (see scheme). cod = 1,5-cyclooctadiene; DME = 1,2-dimethoxyethane.
Enantioselective preparation of a novel chiral 1,2-diamine
Demay, Stéphane,Kotschy, Andras,Knochel, Paul
, p. 863 - 866 (2007/10/03)
A short enantioselective preparation of (1S,2S)-trans-1,2-diamino-3-cyclohexene using a double [3,3]-sigmatropic rearrangement of an allylic bis(imidate) is described (Overman rearrangement). The starting chiral diol is conveniently obtained by enzymatic resolution.
