352019-92-2

Upstream product

• 28165-49-3 6-bromoguaiacol 
• 7368-78-7 4-bromoguaiacol 
• 352020-04-3 2-methoxy-4-bromophenol allyl ether 
• 106-95-6 allyl bromide 
• 90-05-1 2-methoxy-phenol 

Downstream Products

• 1384190-36-6 2-allyl-4-bromo-6-methoxyphenol 3'-methoxy-4'-benzyloxybenzyl ether 
• 1384190-46-8 2-{2-[4-(benzyloxy)-3-methoxybenzyloxy]-5-bromo-3-methoxyphenyl}acetaldehyde 
• 1206902-68-2 2-{2-[4-(benzyloxy)-3-methoxybenzyloxy]-5-bromo-3-methoxyphenyl}acetic acid 
• 1384190-45-7 C₂₅H₂₇BrO₆ 
• 1384190-48-0 C₃₇H₃₈BrNO₇ 
• 1384190-37-7 C₃₇H₃₆BrN₃O₇ 
• 1384190-38-8 C₃₇H₃₆BrNO₇ 
• 352019-96-6 (4S)-4-benzyl-3-[(2S,3S)-2-(2-benzyloxy-5-bromo-3-methoxyphenyl)-3-(4-benzyloxy-3-methoxyphenyl)-3-hydroxypropionyl]-2-oxazolidinone 
• 352020-01-0 (2S,3R)-2-(4-tert-butyldimethylsilyloxy-3-methoxyphenyl)-3-tert-butyldimethylsilyloxymethyl-2,3-dihydro-5E-(3-ethoxy-3-oxo-1-propenyl)-7-methoxybenzo[b]furan 
• 352019-97-7 (1S,2R)-2-(2-benzyloxy-5-bromo-3-methoxyphenyl)-1-(4-benzyloxy-3-methoxyphenyl)-1,3-propanediol 
• 352020-00-9 (2S,3R)-2-(4-tert-butyldimethylsilyloxy-3-methoxyphenyl)-3-tert-butyldimethylsilyloxymethyl-2,3-dihydro-5-formyl-7-methoxybenzo[b]furan 
• 352019-99-9 (2S,3R)-5-bromo-2-(4-tert-butyldimethylsilyloxy-3-methoxyphenyl)-3-tert-butyldimethylsilyloxymethyl-2,3-dihydro-7-methoxybenzo[b]furan 
• 352020-02-1 (2S,3R)-5-[(E)-2-ethoxycarbonylvinyl]-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-hydroxymethyl-7-methoxybenzo[b]furan 
• 352019-95-5 (4S)-4-benzyl-3-[2-(2-benzyloxy-5-bromo-3-methoxyphenyl)acetyl]-2-oxazolidinone 

Relevant academic research and scientific papers

Investigating the microwave-accelerated Claisen rearrangement of allyl aryl ethers: Scope of the catalysts, solvents, temperatures, and substrates

The microwave-accelerated Claisen rearrangement of allyl aryl ethers was investigated, in order to gain insight into the scope of the catalysts, solvents, temperatures, and substrates. Among the catalysts examined, phosphomolybdic acid (PMA) was found to greatly accelerate the reaction in NMP, at temperatures ranging from 220 to 300 °C. This method was found to be useful for preparing several intermediates previously reported in the literature using precious metal catalysts such as Au(I), Ag(I), and Pt(II). Additionally, substrates bearing bromo and nitro groups on the aryl portion required careful tailoring of the reaction conditions to avoid complex product profiles.

A short-step asymmetric synthesis of dehydrodiconiferyl alcohol via C-H insertion reaction

A rhodium-catalyzed intramolecular C-H insertion reaction using a chiral auxiliary and a chiral catalyst was employed to achieve double asymmetric induction of a trans-disubstituted dihydrobenzofuran ring, as the key reaction of a stereoselective synthesis of (-)-dehydrodiconiferyl alcohol in 13 steps from commercially available guaiacol. Georg Thieme Verlag Stuttgart · New York.

Stereoselective synthesis of the neolignan, (+ )-dehydrodiconiferyl alcohol.

A stereo controlled synthesis of the biologically active neolignan, (+)-dehydrodiconiferyl alcohol (1) was achieved. This synthetic method was also efficient for preparing its enantiomer and other derivatives with biological activity.