35203-66-8

Usage

Uses

Used in Polymer Industry:
2,2,6,6-TETRAMETHYL-4-(METHYLSULFONYLOXY)-1-PIPERIDINOOXY is used as a UV stabilizer and antioxidant for protecting polymers from degradation caused by exposure to UV radiation and other environmental factors. This extends the lifespan and durability of various plastic and resin-based products.
Used in Plastics Production:
2,2,6,6-TETRAMETHYL-4-(METHYLSULFONYLOXY)-1-PIPERIDINOOXY is used as a light stabilizer in the production of plastics to enhance their resistance to UV radiation, preventing discoloration, brittleness, and other signs of degradation.
Used in Coatings Industry:
2,2,6,6-TETRAMETHYL-4-(METHYLSULFONYLOXY)-1-PIPERIDINOOXY is used as an additive in coatings to provide UV protection, ensuring the longevity and appearance of coated surfaces by preventing fading, chalking, and other UV-induced damage.
Used in Adhesives Production:
2,2,6,6-TETRAMETHYL-4-(METHYLSULFONYLOXY)-1-PIPERIDINOOXY is used as a stabilizing agent in the formulation of adhesives to improve their resistance to UV radiation, ensuring their performance and durability over time.

InChI:InChI=1/C10H21NO4S/c1-9(2)6-8(15-16(5,13)14)7-10(3,4)11(9)12/h8,12H,6-7H2,1-5H3

Upstream product

• 2403-88-5 4-hydroxy-2,2,6,6-tetramethylpiperidine 
• 826-36-8 2,2,6,6-Tetramethyl-4-piperidone 
• 45985-24-8 TEMPOL 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 14691-88-4 4-amino-2,2,6,6-tetramethyl-1-piperidine-1-oxyl 

Relevant academic research and scientific papers

Radical-functionalised gel: A building-block strategy for magnetochiral assembly

A chiral organogelating scaffold is functionalised with a stable organic radical pendant. The morphology and spectroscopic properties of the gels are investigated as a function of the organogelator concentration and temperature. The combination of AFM and ESR spectroscopy provides firm evidence that the architecture responsible for the formation of the macroscopic gel (i.e., the fibrillar structure) is maintained below the gelling concentration. This opens relevant perspectives in terms of the realisation of complex supramolecular chiral structures incorporating paramagnetic functions, and demonstrates that the ESR technique is suitable as a fast and direct check of the sample state (gel, solution, or small aggregates). A radically new gel: AFM and ESR spectroscopic studies are used to investigate a radical-functionalised gel and the gelation process (see graph). The analyses also provide evidence that the fibrillar structure is maintained below the gelling concentration. This opens relevant perspectives in terms of the realization of complex supramolecular chiral structures incorporating paramagnetic functions.

Preparation and spectroscopic, magnetic, and electrochemical studies of mono-/biradical TEMPO derivatives

A comparison set of mono-/biradical TEMPO derivatives was prepared, novel compounds were fully characterized, and their physicochemical properties were determined. Cyclic voltammetry revealed reversible redox behavior for all studied nitroxides. Moreover, the electron-withdrawing substituents increased the oxidation potential of the respective nitroxides in comparison to electron-donating groups. While EPR spectra of monoradicals in dichloromethane at 295 K reveal the expected three-line signal, spectra of biradicals show more complex features. DFT and MP2 calculations indicate that the EPR splitting pattern of dinitroxide 7 could be explained by its interactions with solvent molecules. In the solid state, mononitroxides 4 and 5 behave as a Heisenberg antiferromagnetic chain, whereas dinitroxides 6-8 are almost isolated paramagnetic diradicals coupled in an antiferromagnetic manner.

Interaction of Photogenerated Spin Qubit Pairs with a Third Electron Spin in DNA Hairpins

The designing of tunable molecular systems that can host spin qubits is a promising strategy for advancing the development of quantum information science (QIS) applications. Photogenerated radical pairs are good spin qubit pair (SQP) candidates because th

2′-Alkynylnucleotides: A Sequence- and Spin Label-Flexible Strategy for EPR Spectroscopy in DNA

Electron paramagnetic resonance (EPR) spectroscopy is a powerful method to elucidate molecular structure through the measurement of distances between conformationally well-defined spin labels. Here we report a sequence-flexible approach to the synthesis of double spin-labeled DNA duplexes, where 2′-alkynylnucleosides are incorporated at terminal and internal positions on complementary strands. Post-DNA synthesis copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with a variety of spin labels enable the use of double electron-electron resonance experiments to measure a number of distances on the duplex, affording a high level of detailed structural information.

ANTIOXIDANTS AND METHODS OF THEIR USE

The invention relates to compounds and compositions to treat some neurodegenerative diseases. In some embodiments, the invention relates to an antioxidant comprising a selenium atom and nitroxide group. In further embodiments, the antioxidant comprises peroxidase and superoxide dismutase activity. In some embodiments, the antioxidants are effective in treating neurodegenerative diseases including, but not limited to, Alzheimer's disease, Parkinson's disease, or multiple sclerosis. In additional embodiments, the invention relates to using compounds disclosed herein as free radical electromagnetic imaging agents.

A Simple Synthesis of 4-Amino-2,2,6,6-tetramethyl-1-piperidinyloxy Radical

A simple synthesis of the title compound starting from 4-hydroxy-2,2,6,6-tetramethyl-1-piperidyloxy radical (2) based on sulfonate-azide exchange method is described.