35218-98-5Relevant academic research and scientific papers
Synthesis of substituted uracils by the reactions of halouracils with selenium, sulfur, oxygen and nitrogen nucleophiles under focused microwave irradiation
Fang, Woei-Ping,Cheng, Yuh-Tsyr,Cheng, Yann-Ru,Cherng, Yie-Jia
, p. 3107 - 3113 (2007/10/03)
Under microwave irradiation, the nucleophilic substitution reactions of halouracils with selenium, sulfur, oxygen and nitrogen nucleophiles was complete within several minutes with yields up to 99%. The method using microwave irradiation is superior to th
Reductive Debromination and Coupling Reaction in the Thermolysis of 5-Bromouracils in N,N-Dialkylamides. Cleavage of the C(5)-Bromine bond by an Initial Electron-transfer Process
Sako, Magiochi,Suzuki, Mikio,Tanabe, Miyuki,Maki, Yoshifumi
, p. 3114 - 3117 (2007/10/02)
Thermolysis of various 5-bromouracils (1) in N,N-dialkylamides results in the formation of methylenebisuracils (2) and reductive debrominated products (3) via cleavage of the C(5)-Br bond; the latter involves a one-electron transfer process.The product distribution between (2) and (3) depends upon the nature of substituents in the uracil ring.
