3522-07-4 Usage
General Description
6-Methoxy-1H-indazole is a chemical compound with the molecular formula C9H8N2O. It belongs to the indazole class of chemicals and contains a methoxy group attached to the 6-position of the indazole ring. 6-Methoxy-1H-indazole has potential applications in medicinal chemistry research, particularly in the development of pharmaceutical drugs. Indazole derivatives, including 6-Methoxy-1H-indazole, have been studied for their various biological activities, including anticancer, anti-inflammatory, and antimicrobial properties. 6-Methoxy-1H-indazole is also of interest in the field of synthetic chemistry as a building block for the synthesis of other indazole derivatives with potential pharmacological activities. Overall, 6-Methoxy-1H-indazole is a versatile chemical compound with potential applications in pharmaceutical and research purposes.
Check Digit Verification of cas no
The CAS Registry Mumber 3522-07-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,5,2 and 2 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 3522-07:
(6*3)+(5*5)+(4*2)+(3*2)+(2*0)+(1*7)=64
64 % 10 = 4
So 3522-07-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H8N2O/c1-11-7-3-2-6-5-9-10-8(6)4-7/h2-5H,1H3,(H,9,10)
3522-07-4Relevant articles and documents
Palladium-catalyzed hydrodefluorination of fluoroarenes
Brodney, Michael A.,Gair, Joseph J.,Giroux, Simon,Grey, Ronald L.
, p. 131 - 146 (2021/06/18)
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Palladium catalyzed hydrodefluorination of fluoro-(hetero)arenes
Gair, Joseph J.,Grey, Ronald L.,Giroux, Simon,Brodney, Michael A.
supporting information, p. 2482 - 2487 (2019/04/10)
Palladium catalyzed hydrodefluorination was developed for fine-tuning the properties of fluoro-(hetero)aromatic compounds. The robust reaction can be set up in air, requires only commercially available components, and tolerates a variety of heterocycles and functionalities relevant to drug discovery. Given the prevalence of fluorine incorporation around metabolic hotspots, the corresponding deuterodefluorination reaction may prove useful for converting fluorinated libraries to deuterated analogues to suppress the oxidative metabolism by kinetic isotope effects.
MUSCARINIC AGONISTS
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Paragraph 0223, (2014/10/04)
Compounds of formula (I) and methods are provided for the treatment of disease or conditions in which modification of cholinergic, especially muscarinic receptor activity, has a beneficial effect.
