352209-81-5Relevant academic research and scientific papers
Method for preparing alpha-sulfonyl hydroxamic acid derivatives
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, (2008/06/13)
Compounds of the formula: that can be important as matrix metalloproteinase (MMP) and TNF-alpha converting enzyme (TACE) inhibitors, phosphodiesterase inhibitors, renin inhibitors, antithrombotics, and 5-lipoxygenase inhibitors are prepared by novel methods of the present invention.
An efficient method to prepare α-sulfonyl hydroxamic acid derivatives
Sandanayaka, Vincent P.,Zask, Arie,Venkatesan, Aranapakam M.,Baker, Jannie
, p. 4605 - 4607 (2007/10/03)
α-Sulfonyl hydroxamic acid derivatives are biologically important molecules. An efficient protocol has been developed to make these molecules via a direct sulfonylation of enolates. Several piperidine containing α-sulfonyl hydroxamic acid compounds have been prepared by this procedure.
