35221-08-0

Basic information

• Product Name: 1H-Pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione, 5,7-dimethyl-3-phenyl-
• CAS NO: 35221-08-0
• Molecular Formula: C13H12N4O2
• Molecular Weight: 256.264
• Mol File: 35221-08-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione, 5,7-dimethyl-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione, 5,7-dimethyl-3-phenyl-(35221-08-0)
• EPA Substance Registry System: 1H-Pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione, 5,7-dimethyl-3-phenyl-(35221-08-0)

Safety Data

• Hazardous Substances Data: 35221-08-0(Hazardous Substances Data)

Upstream product

• 6972-27-6 1,3-Dimethyl-6-chlorouracil 
• 725-12-2 2,5-bis-(phenyl)-1,3,4-oxadiazole 
• 52421-32-6 6-(benzylidene-1'-methylhydrazino)-1,3-dimethyluracil 
• 123506-40-1 6-hydrazino-1,3-dimethyl-1H-pyrimidine-2,4-dione 
• 100-52-7 benzaldehyde 
• 538-51-2 benzylidene phenylamine 
• 99261-94-6 6,8-Dimethyl-3-phenyl-1H,8H-pyrimido[4,5-e][1,3,4]thiadiazine-5,7-dione 
• 25774-97-4 6-benzylidenehydrazino-1,3-dimethyluracil 
• 2025-40-3 ethyl benzylidenecyanoacetate 
• 709-79-5 2-cyano-3-phenylacrylamide 
• 2700-22-3 Benzylidenemalononitrile 

Relevant articles and documents

Synthesis of 4-trifluoromethylpyrimido[4,5-c]-pyridazine-5,7-dignes from uracils

The reaction of 6-hydrazinouracils (1) with 3-aryl-1,1,1-trifluoropropane-2,3-dione monohydrates (2) in refluxing ethanol in the presence of p-toluenesulfonic acid gave regioselectively 3-aryl-4-trifluoromethyl-5,6,7,8-tetrahydropyrimido[4,5-c]pyridazine-

Studies on Uracils. 10. A Facile One-Pot Synthesis of Pyrido- and Pyrazolopyrimidines

The reaction of functionalised uracils bearing amino and hydroxyamino groups at C-6 position (4 and 5) with strongly electrophilic cyano olefins (1,2 and 3) gave rise to pyridopyrimidines 7-9 in excellent yields.Hydrazine-substituted uracil 6 gave access to an efficient one-step synthesis of pyrazolopyrimidines 10.The capture of an eliminated hydrogen molecule by cyano olefins in the case of their reaction with 4 and 6 was confirmed by the isolation of dihydrocyano olefins.This fact further supported the plausible mechanism for the formation of compounds 7-10 via dihydropyrido- and dihydropyrazolopyrimidine intermediates A and C.

N-Bromosuccinimide in Heterocyclic Synthesis. Synthesis of Pyrazolopyrimidines, Pyrimido-as-triazines, and Pyrimidopyridazines from 6-Arylidenehydrazino-1,3-dimethyluracil Derivatives

Reactions of 6-arylidenehydrazino-1,3-dimethyluracil derivatives with N-bromosuccinimide leading to pyrazolopyrimidines, pyrimido-as-triazines, and pyrimidopyridazines are described.