35228-99-0

Basic information

• Product Name: 1H-Pyrazol-4-ol, 1-methyl-3,5-diphenyl-
• CAS NO: 35228-99-0
• Molecular Formula: C16H14N2O
• Molecular Weight: 250.3
• Mol File: 35228-99-0.mol

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazol-4-ol, 1-methyl-3,5-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazol-4-ol, 1-methyl-3,5-diphenyl-(35228-99-0)
• EPA Substance Registry System: 1H-Pyrazol-4-ol, 1-methyl-3,5-diphenyl-(35228-99-0)

Safety Data

• Hazardous Substances Data: 35228-99-0(Hazardous Substances Data)

Upstream product

• 17952-96-4 2,5-diphenyl-3,4-diazacyclopentadienone 3,4-dioxide 
• 121-45-9 phosphorous acid trimethyl ester 
• 17953-08-1 2,5-diphenyl-3,4-diazacyclopentadienone 3-oxide 
• 1074-12-0 phenylglyoxal hydrate 
• 13466-29-0 benzaldehyde N-methyl hydrazone 

Downstream Products

• 60628-01-5 4-butoxy-1-methyl-3,5-diphenyl-1H-pyrazole 
• 60628-00-4 3,5-Diphenyl-1-methyl-4-n-propoxypyrazole 
• 60660-03-9 4-(4-chloro-phenoxy)-1-methyl-3,5-diphenyl-1H-pyrazole 
• 60628-10-6 4-(1-methyl-3,5-diphenyl-1H-pyrazol-4-yloxy)-aniline 
• 60628-09-3 1-methyl-4-(4-nitro-phenoxy)-3,5-diphenyl-1H-pyrazole 
• 60628-02-6 4-heptyloxymethoxy-1-methyl-3,5-diphenyl-1H-pyrazole 
• 34765-45-2 1-methyl-3,5-diphenyl-4-acetoxypyrazole 
• 130188-25-9 1-Diethylamino-3-(1-methyl-3,5-diphenyl-1H-pyrazol-4-yloxy)-propan-2-ol 
• 130188-22-6 1-Isopropylamino-3-(1-methyl-3,5-diphenyl-1H-pyrazol-4-yloxy)-propan-2-ol 
• 130188-24-8 1-Dimethylamino-3-(1-methyl-3,5-diphenyl-1H-pyrazol-4-yloxy)-propan-2-ol 
• 130188-23-7 1-Isobutylamino-3-(1-methyl-3,5-diphenyl-1H-pyrazol-4-yloxy)-propan-2-ol 
• 130188-29-3 1-(1-Methyl-3,5-diphenyl-1H-pyrazol-4-yloxy)-3-(4-methyl-piperazin-1-yl)-propan-2-ol 
• 130188-28-2 1-(1-Methyl-3,5-diphenyl-1H-pyrazol-4-yloxy)-3-morpholin-4-yl-propan-2-ol 
• 130188-27-1 1-(1-Methyl-3,5-diphenyl-1H-pyrazol-4-yloxy)-3-piperidin-1-yl-propan-2-ol 

Relevant articles and documents

Reductive methylation/phosphorylation of 3,4-diazacyclopentadienone N-oxides with trimethyl phosphite

Treatment of 2,5-diphenyl-3,4-diazacyclopentadienone 3-oxide and 3,4-dioxide with trimethyl phosphite results in N-deoxygenation and methylation and O-phosphorylation to produce dimethyl (1-methyl-3,5-diphenyl-4-pyrazolyl) phosphate.

Reactions of Glyoxals with Hydrazones: A New Route to 4-Hydroxypyrazoles

N-Substituated hyrazones of aldehydes react with glyoxals under non-aqueous conditions to give N-substituted 4-hydroxypyrazoles; fourteen such products are described.In the presence of water, N-substituted 3-acyl-4-hydroxypyrazoles are produced from 2-oxoaldehyde hydrazones and glyoxals.It is shown that glyoxals combine in a 1:1 ratio with N-monosubstituted hydrazones to give 2-hydrazonoaldehydes as the kinetically controlled products.At room temperature or lower, these hydrazonoaldehydes rearrange to the more stable 2-oxoaldehyde hydrazones and react with glyoxals to give N-substituted 3-acyl-4-hydroxypyrazoles; sixteen such products are described.This synthesis, involving easily accessible starting materials, opens up a new, and for certain derivatives exclusive, route to 4-hydroxypyrazoles.

Novel process for the preparation of 3,5-diphenyl-4-pyrazolol and certain derivatives thereof

There is provided a method for the preparation of 3,5-diphenyl-4-pyrazolol and certain derivatives thereof which are useful as intermediates for the preparation of 4-alkoxy and 4-benzyloxypyrazolium herbicides and fungicides.