35264-98-3Relevant articles and documents
3-amino-4-hydroxy-L(-)-butyramide hydrochloride.
Keresztesy Jr.,Zambito,Babson
, p. 1142 - 1143 (1971)
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Method for synthesizing chiral 4-(N-carbobenzoxy) pyrrolidone
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, (2019/10/01)
The invention provides a method for synthesizing chiral 4-(N-carbobenzoxy) pyrrolidone. L-asparaginate is adopted as an initial raw material, through four steps of reactions of amino protection, diazo-reactions, carbonyl reduction and cyclization, chiral 4-(N-carbobenzoxy) pyrrolidone is prepared, raw materials are low in price and easy to obtain, chiral resolution is not needed in the reaction process, the yield is high, the reaction speed is rapid, a small amount of byproducts are generated, and the method is very applicable to industrial application.