36983-58-1

Basic information

• Product Name: (3S)-3-amino-4-hydroxybutanamide
• Synonyms: L-Asparaginol;(3S)-3-Amino-4-hydroxybutanamide
• CAS NO: 36983-58-1
• Molecular Formula: C₄H₁₀N₂O₂
• Molecular Weight: 118.1344
• Mol File: 36983-58-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 433°C at 760 mmHg
• Flash Point: 215.7°C
• Density: 1.218g/cm³
• Vapor Pressure: 2.57E-09mmHg at 25°C
• Refractive Index: 1.513
• CAS DataBase Reference: (3S)-3-amino-4-hydroxybutanamide(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-3-amino-4-hydroxybutanamide(36983-58-1)
• EPA Substance Registry System: (3S)-3-amino-4-hydroxybutanamide(36983-58-1)

Safety Data

• Hazardous Substances Data: 36983-58-1(Hazardous Substances Data)

Usage

General Description

(3S)-3-amino-4-hydroxybutanamide is a chemical compound with the molecular formula C4H10N2O2. It is an organic compound that contains an amino group and a hydroxy group, making it classified as an amino alcohol. (3S)-3-amino-4-hydroxybutanamide is also known as threoninol or threitolamine and is derived from the amino acid threonine. It has a 3S stereochemistry, meaning that the hydroxy and amino groups are located on the third carbon atom of the butanamide chain. (3S)-3-amino-4-hydroxybutanamide is commonly used in biochemical and pharmaceutical research due to its role as a building block in the synthesis of various molecules and compounds. It may also have potential applications in the development of pharmaceutical drugs and medical treatments.

Upstream product

• 70-47-3 L-asparagine 
• 137428-35-4 (S)-(+)-(N,N-dibenzoylamino)-4-hydroxy-butanecarboxamide 
• 30044-67-8 L-t-Boc-Asnol 
• 76-05-1 trifluoroacetic acid 
• 35264-98-3 3-Carbobenzoxyamino-4-hydroxy-L-butyramid 

Relevant articles and documents

Method for synthesizing moxifloxacin and derivatives thereof

The invention provides a method for synthesizing moxifloxacin and derivatives thereof. Aminopyrrolidone derivatives are constructed to further obtain (S,S)-2,8-diazo-bicyclo[4.3.0]nonane so as to synthesize the moxifloxacin and the derivatives thereof. The method has the beneficial effects that raw materials are wide in source and low in price; chiral resolution is not needed in a preparation process; the yield and purity are relatively high; the process cost is further reduced; obvious economic value is achieved.

Synthetic method for moxifloxacin chiral side chain intermediate

The invention provides a synthetic method for a moxifloxacin chiral side chain intermediate. The method provided by the invention uses an easily-available and inexpensive L-asparagine as a starting material to obtain the moxifloxacin chiral side chain intermediate through an eight-step reaction; and the whole route has novel design and avoids a chiral separation process adopted by most routes, andthe method has higher practicability, a high yield, a quick reaction speed and few by-products, and is very suitable for industrial application.

Rotihibins, novel plant growth regulators from Streptomyces graminofaciens

In the course of screening search for plant growth regulators, a culture filtrate of Streptomyces graminofaciens 3C02 was found to inhibit the growth of lettuce seedlings. The active substances, named rotihibin A (1) and B (2), were revealed to be lipo-peptidal compounds. Rotihibins inhibit growth of various plants at below 1 μg/ml, but do not show lethal activity even at higher doses.