4668-37-5

Basic information

• Product Name: Z-ASN-OME
• Synonyms: N-ALPHA-CARBOBENZOXY-L-ASPARAGINE METHYL ESTER;Z-L-ASPARAGINE METHYL ESTER;Z-ASN-OME;Z-ASPARAGINE-OME;N-Benzyloxycarbonylasparagine methyl ester;N-Carbobenzoxy-L-asparagine methyl ester;N2-Benzyloxycarbonyl-L-asparagine methyl ester;Nα-Z-L-asparagine methyl ester≥ 99% (TLC)
• CAS NO: 4668-37-5
• Molecular Formula: C₁₃H₁₆N₂O₅
• Molecular Weight: 280.28
• Mol File: 4668-37-5.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Storage Temp.: -15°C
• CAS DataBase Reference: Z-ASN-OME(CAS DataBase Reference)
• NIST Chemistry Reference: Z-ASN-OME(4668-37-5)
• EPA Substance Registry System: Z-ASN-OME(4668-37-5)

Safety Data

• Hazardous Substances Data: 4668-37-5(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Upstream product

• 107-31-3 Methyl formate 
• 2304-96-3 N-benzyloxycarbonyl-L-asparagine 
• 74-88-4 methyl iodide 
• 684-93-5 1-methyl-1-nitrosourea 
• 501-53-1 benzyl chloroformate 
• 100-51-6 benzyl alcohol 
• 67-56-1 methanol 
• 186581-53-3 diazomethane 

Downstream Products

• 35264-98-3 3-Carbobenzoxyamino-4-hydroxy-L-butyramid 
• 60684-59-5 methyl (S)-2-(((benzyloxy)carbonyl)amino)-4-oxobutanoate 
• 1417900-10-7 (4S)-4-[(benzyloxycarbonyl)amino]-4,5-dihydro-3(2H)-pyridazinone 
• 1417900-12-9 (4S)-4-[(benzyloxycarbonyl)amino]-tetrahydro-3(2H)-pyridazinone 
• 1417900-13-0 (4S)-4-[(benzyloxycarbonyl)amino]-2-methyl-tetrahydro-3(2H)-pyridazinone 
• 1417900-14-1 (4S)-4-[(benzyloxycarbonyl)amino]-tetrahydro-3-oxo-1(2H)-pyridazinecarboxamide 
• 1417900-15-2 (4S)-4-[(benzyloxycarbonyl)amino]-tetrahydro-2-methyl-3-oxo-1(2H)-pyridazinecarboxamide 
• 1417900-19-6 (4S)-4-[(benzyloxycarbonyl)amino]tetrahydro-2-methyl-3-oxo-1(2H)-pyridazinecarbonitrile 
• 314728-04-6 (S)-2-benzyloxycarbonylamino-4-hydroxybutyric acid methyl ester 
• 60846-91-5 3-(S)-N-benzyloxycarbonylaminopyrrolidine-2,5-dione 
• 168399-08-4 methyl 3-benzyloxycarbonyl-2-oxo-imidazolidine-4(S)-carboxylate 

Relevant articles and documents

Method for synthesizing chiral 4-(N-carbobenzoxy) pyrrolidone

The invention provides a method for synthesizing chiral 4-(N-carbobenzoxy) pyrrolidone. L-asparaginate is adopted as an initial raw material, through four steps of reactions of amino protection, diazo-reactions, carbonyl reduction and cyclization, chiral 4-(N-carbobenzoxy) pyrrolidone is prepared, raw materials are low in price and easy to obtain, chiral resolution is not needed in the reaction process, the yield is high, the reaction speed is rapid, a small amount of byproducts are generated, and the method is very applicable to industrial application.

An access to aza-Freidinger lactams and E-locked analogs

Freidinger lactams, possessing a peptide bond configuration locked to Z, are important key elements of conformationally restricted peptidomimetics. In the present work, the CαHi+1 unit has been replaced by N, leading to novel aza-Fre

Utility of tetrathiomolybdate and tetraselenotungstate: Efficient synthesis of cystine, selenocystine, and their higher homologues

Efficient synthesis of cystine, selenocystine, and their higher homologues like homo and bishomo amino acid derivatives from natural amino acid derivatives using tetrathiomolybdate and tetraselenotungstate reagents under mild and neutral conditions is reported. The generality of the reaction has been studied by capping various groups to amino and carboxyl components of canonical amino acids.