3532-29-4Relevant academic research and scientific papers
Microwave-Accelerated N-Acylation of Sulfoximines with Aldehydes under Catalyst-Free Conditions
Ambala, Srinivas,Arvidsson, Per I.,Govender, Thavendran,Kruger, Hendrik G.,Naicker, Tricia,Rajbongshi, Kamal K.
, p. 1279 - 1286 (2020/04/15)
An efficient catalyst-free radical cross-coupling reaction between aromatic aldehydes and sulfoximines was developed. The reaction took place in the presence of N-bromosuccinimide as the radical initiator under microwave irradiation to afford the corresponding acylated sulfoximines in moderate to excellent yields (27 examples). This protocol proved to be rapid, easy to handle, and applicable to a broad scope of substrates.
The copper-catalyzed oxidative N-acylation of sulfoximines
Wang, Long,Priebbenow, Daniel L.,Zou, Liang-Hua,Bolm, Carsten
supporting information, p. 1490 - 1494 (2013/06/27)
An oxidative cross-coupling reaction between aldehydes and sulfoximines involving dual C-H/N-H functionalization has been developed. This reaction process is facilitated by a simple copper catalyst (1 mol% loading) and tert-butyl hydroperoxide (TBHP) as the oxidant and proceeds under mild reaction conditions to afford a series of valuable N-acylated sulfoximine derivatives in excellent yields. Copyright
Carbamoylsulphoximides as protein kinase inhibitors
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Page/Page column 26, (2008/12/06)
The invention relates to carbamoylsulphoximides as protein kinase inhibitors of the general formula 1.
