3532-69-2

Usage

Uses

Used in Pharmaceutical Industry:
3-hydroxy-2-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-isoindol-1-one is utilized as a pharmacological agent for its potential biological activities. Its unique structure may contribute to the development of new drugs, targeting various medical conditions.
Used as a Precursor in Chemical Synthesis:
In the chemical industry, 3-hydroxy-2-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-isoindol-1-one serves as a precursor for synthesizing other complex organic compounds, contributing to the creation of novel materials and substances.
Used in Chemical Research:
3-hydroxy-2-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-isoindol-1-one is employed as a research tool in chemical reactions and molecular interactions studies. Its properties can provide insights into reaction mechanisms and the behavior of similar compounds in various scientific fields.

Upstream product

• 85-52-9 2-Benzoylbenzoic acid 
• 104-94-9 4-methoxy-aniline 
• 2142-04-3 2-(4-methoxyphenyl)isoindoline-1,3-dione 
• 93-58-3 benzoic acid methyl ester 
• 7472-54-0 N-(p-methoxyphenyl)benzamide 
• 85-44-9 phthalic anhydride 
• 612-35-1 2-Benzylbenzoic acid 
• 55810-66-7 2-(benzyl)benzoyl chloride 

Downstream Products

• 903826-36-8 2-benzoyl-N-(4-methoxyphenyl)benzamide 
• 36503-83-0 1-oxo-2,4-diphenylphthalazine 
• 294629-57-5 methyl 2-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-isoindol-1-on-3-acetate 
• 294629-37-1 diethyl 2-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-isoindol-1-on-3-malonate 
• 294629-53-1 2-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-isoindol-1-on-3-acetic acid 

Relevant academic research and scientific papers

Copper-catalyzed aerobic double functionalization of benzylic C(sp3)-H bonds for the synthesis of 3-hydroxyisoindolinones

A copper-catalyzed aerobic 3-hydroxyisoindolinone synthesis was developed via the benzylic double C(sp3)-H functionalization of 2-alkylbenzamides. In this reaction, molecular oxygen was used as both an oxidant for C(sp3)-H functionalization and an oxygen source. Our method can be extended to diverse benzylic C(sp3)-H bonds and shows excellent functional group tolerance. This journal is

Hydrogenolysis of the C-O bond of hydroxylactams as a convenient method for the synthesis of substituted isoindolin-1-ones

A simple and efficient method for the synthesis of isoindolin-1-ones containing alkyl or aryl substituents at positions 2 and (or) 3 was suggested. The method is based on the earlier unknown Pd0-catalyzed hydrogenolysis of hydroxylactams.

Application of organolithium and related reagents in synthesis. Part 23: Synthetic strategies based on ortho-aromatic metallation. Synthesis of 4b- arylisoindolo[2,1-a]quinoline derivatives

The synthesis of the 2-aryl-3-hydroxyisoindol-1-ones 3 and their successive conversion via the reaction with 1-methoxy-1- trimethylsilyloxyethene in the presence of titanium(IV) chloride into 3- carboxymethylphthalimides 7 and subsequent cyclization via sequential treatment with oxalyl chloride and aluminium chloride as a way of regiospecific transformation of the benzenecarbocylic acids into the corresponding isoindolo[2,1-a]quinoline-5, 11-diones 5 is described. (C) 2000 Elsevier Science Ltd.