353273-45-7

Basic information

• Product Name: 3-benzylideneamino-1H-pyrazolo[3,4-b]quinoline
• Synonyms: 3-benzylideneamino-1H-pyrazolo[3,4-b]quinoline
• CAS NO: 353273-45-7
• Molecular Weight: 272.309
• Mol File: 353273-45-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-benzylideneamino-1H-pyrazolo[3,4-b]quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzylideneamino-1H-pyrazolo[3,4-b]quinoline(353273-45-7)
• EPA Substance Registry System: 3-benzylideneamino-1H-pyrazolo[3,4-b]quinoline(353273-45-7)

Safety Data

• Hazardous Substances Data: 353273-45-7(Hazardous Substances Data)

Upstream product

• 95104-21-5 2-chloroquinoline-3-carbonitrile 
• 116704-96-2 3-Hydroxyiminomethylquinoline-2(1H)-one 
• 73568-25-9 2-chloro-3-quinoline carboxaldehyde 
• 106835-44-3 1H‐pyrazolo[3,4‐b]quinolin‐3‐amine 
• 100-52-7 benzaldehyde 
• 91301-03-0 3-formyl-2-quinolone 
• 36926-82-6 2-oxo-1,2-dihydroquinoline-3-carbonitrile 

Relevant articles and documents

Synthesis of new pyrazolo[3,4-b]quinolines, thieno[2,3-b]quinolines and related condensed heterocyclic systems

3-Amino-l H-pyrazolo[3,4-b]quinoline (2) was reacted with benzaldehyde, acetylacetone, ethyl aceto-acetate and/or phenyl isothiocyanate to give compounds 3,4,5 and 6, respectively. The interaction of 6 with some α-haloesters and/or α-haloketones produced the corresponding thiazolidinones 7a-c and thiazolines 9a-d. lH-Pyrazolo[3,4-b]quinoline-3-diazonium chloride (11) was coupled with some active methylene compounds to give the corresponding hydrazono compounds 12a, b and 13 which, in turn were cyclized into the corresponding triazinopyrazoloquinolines 14a,b and 15 by heating in acetic acid. 3-Aminothieno[2,3-b]quinoline-2-carbohydrazide (19) and 3-amino-2-(1H-benzimidazol-2-yl)thieno[2,3-b]quinoline (21) were prepared and employed as key intermediates for synthesizing the second class of the title compounds.