353288-19-4

Basic information

• Product Name: 3-(4-fluorophenyl)-6-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
• Synonyms: 3-(4-fluorophenyl)-6-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
• CAS NO: 353288-19-4
• Molecular Formula: C15H9FN4S
• Molecular Weight: 296.3221632
• Mol File: 353288-19-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.46±0.1 g/cm3(Predicted)
• PKA: -1.06±0.50(Predicted)
• CAS DataBase Reference: 3-(4-fluorophenyl)-6-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-fluorophenyl)-6-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(353288-19-4)
• EPA Substance Registry System: 3-(4-fluorophenyl)-6-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(353288-19-4)

Safety Data

• Hazardous Substances Data: 353288-19-4(Hazardous Substances Data)

Upstream product

• 61019-29-2 C₈H₆FN₂OS₂^(1-)*K⁽¹⁺⁾ 
• 61019-25-8 4-amino-5-(3-fiuorophenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thiol 
• 65-85-0 benzoic acid 
• 403-33-8 methyl 4-flurobenzoate 
• 456-06-4 4-fluorobenzoyl hydrazide 

Relevant articles and documents

3. 6 - Disubstituted [1, 2, 4] triazolo [3, 4 - b] [1, 3, 4] thiadiazole compound and use thereof

The invention discloses 3,6-disubstituted[1,2,4]triazolyl[3,4-b][1,3,4]thiadiazole compounds represented by general formula (I), and pharmaceutically acceptable salts or pharmaceutically acceptable solvates thereof. The compounds can be used as a transpeptidase SrtA inhibitor of Staphylococcus aureus, Bacillus pyogenes, Bacillus anthracis, Streptococcus pneumoniae and other Gram-positive bacteria, and can be used to prepare drugs for treating pathogen infection diseases with the transpeptidase SrtA of the Gram-positive bacteria, such as Staphylococcus aureus, Bacillus pyogenes, Bacillus anthracis and Streptococcus pneumoniae as target. The compounds avoid selection pressure induced drug resistance of pathogens to a certain degree, and mitigate threat of continuous drug-resistant pathogens to the health of human.