3538-69-0

Basic information

• Product Name: (2E)-3-phenylprop-2-enehydrazide
• Synonyms: (2E)-3-Phenylacrylohydrazide; 2-propenoic acid, 3-phenyl-, hydrazide, (2E)-
• CAS NO: 3538-69-0
• Molecular Formula: C₉H₁₀N₂O
• Molecular Weight: 162.1885
• Mol File: 3538-69-0.mol
• Article Data: 34

Chemical Properties

• Density: 1.158g/cm³
• Refractive Index: 1.621
• CAS DataBase Reference: (2E)-3-phenylprop-2-enehydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-3-phenylprop-2-enehydrazide(3538-69-0)
• EPA Substance Registry System: (2E)-3-phenylprop-2-enehydrazide(3538-69-0)

Safety Data

• Hazardous Substances Data: 3538-69-0(Hazardous Substances Data)

Usage

General Description

(2E)-3-phenylprop-2-enehydrazide is a chemical compound with the molecular formula C9H10N2O. It is a hydrazide derivative of (2E)-3-phenylprop-2-enoic acid and has a phenyl group attached to the third carbon of the carbon chain. (2E)-3-phenylprop-2-enehydrazide has potential applications in the field of organic synthesis and pharmaceuticals due to its hydrazide functional group, which is a common moiety in many bioactive molecules. It may also have potential use as a starting material for the synthesis of other organic compounds with biological activity. The properties, uses, and potential hazards of (2E)-3-phenylprop-2-enehydrazide should be thoroughly investigated and understood before its use in any application.

Upstream product

• 108761-28-0 (carbonic acid ethyl ester)-cinnamic acid-anhydride 
• 103-36-6 ethyl 3-phenyl-2-propenoate 
• 102-92-1 cinnamoyl chloride 
• 138292-09-8 (E)-3-Phenyl-acrylic acid benzotriazol-1-yl ester 
• 140-10-3 (E)-3-phenylacrylic acid 
• 100-52-7 benzaldehyde 
• 328012-09-5 (E)-1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-phenylprop-2-en-1-one 
• 103-26-4 Methyl cinnamate 
• 63073-96-1 potassium cinnamate 
• 102-92-1 Cinnamoyl chloride 
• 541-41-3 chloroformic acid ethyl ester 
• 140935-01-9 cyanomethyl trans-cinnamate 
• 103-26-4 methyl cinnamate 
• 23776-87-6 2,5-dioxopyrrolidin-1-yl 3-phenyl acrylate 

Downstream Products

• 192199-01-2 1-styrylamido-7-hydroxy-2-oxo-4-methylquinoline 
• 621-79-4 cinnamamide 
• 25330-03-4 N-(2-Chlor-benzyliden)-N'-cinnamoyl-hydrazin 
• 101350-34-9 N'-benzylidene-3-phenylacrylohydrazide 
• 1352331-74-8 5-methyl-2-styryl-1,3,4-oxadiazole 
• 23571-74-6 2-styryl-[1,3,4]oxadiazole 
• 1874-31-3 5-phenyl-2-styryl-1,3,4-oxadiazole 

Relevant articles and documents

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In this work, the polysaccharide carboxymethyl cellulose (CMC) was first activated via periodate oxidation then modified by insertion of photo-active cinnamic acid hydrazide moieties to finally produce the photo-crosslinkable CMC-CM with various extents of functionalizations. The chemical structures of the manufactured polymeric materials were entirely investigated utilizing FTIR, 1H, 13C NMR, and UV-vis spectra. Upon irradiation in UV light, the progress and kinetics of the cross-linking were detected using UV-vis spectra. Moreover, the crystallinity changes before and after chemical modification and subsequent UV irradiation were examined by XRD spectra. Also, the obtained hydrogels with various cross-linking densities were freeze dried to visualize the morphological changes using SEM. In addition, the rheological experiments indicated the improvement of the hydrogel mechanical properties by increasing both UV irradiation time and degree of cinnamate functionalization. The obtained hydrogel exhibited good swelling, gelation and biodegradation properties, which indicate a promising potential in different biomedical applications.

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Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases

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