35426-69-8

Basic information

• Product Name: Carbamic acid, (2-chlorophenyl)-, 1,1-dimethylethyl ester
• CAS NO: 35426-69-8
• Molecular Formula: C11H14ClNO2
• Molecular Weight: 227.691
• Mol File: 35426-69-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Carbamic acid, (2-chlorophenyl)-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (2-chlorophenyl)-, 1,1-dimethylethyl ester(35426-69-8)
• EPA Substance Registry System: Carbamic acid, (2-chlorophenyl)-, 1,1-dimethylethyl ester(35426-69-8)

Safety Data

• Hazardous Substances Data: 35426-69-8(Hazardous Substances Data)

Upstream product

• 507-40-4 tert-butylhypochlorite 
• 103-71-9 phenyl isocyanate 
• 114-38-5 (2-chlorophenyl)urea 
• 1907-33-1 lithium tert-butoxide 
• 3320-83-0 o-chlorophenyl isocyanate 
• 75-65-0 tert-butyl alcohol 
• 36016-38-3 tert-Butyl N-hydroxycarbamate 
• 3422-01-3 tert-butyl phenylcarbamate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 62-53-3 aniline 
• 1538-75-6 2,2-dimethylpropanoic anhydride 
• 95-51-2 o-chloroaniline 

Downstream Products

• 95-51-2 o-chloroaniline 
• 1425794-19-9 2-(2,4-dimethylphenylsulfanyl)phenyl carbamic acid tert-butyl ester 
• 138344-50-0 tert-butyl [1,1′-biphenyl]-2-ylcarbamate 
• 90-41-5 2-phenylaniline 

Relevant articles and documents

PRODUCTION METHOD FOR AMIDATE COMPOUND

A method for producing an amidate compound represented by Formula (3), comprising reacting a urethane compound represented by Formula (1) with a carboxylate compound represented by Formula (2): (in the formulas, A, n, R1, R2, R3, R4, R5, R6, X, and a are as described in the Description).

Palladium-Catalyzed Decarboxylative Synthesis of Arylamines

A novel approach has been developed for the synthesis of arylamines via the palladium-catalyzed intramolecular decarboxylative coupling (IDC) of aroyloxycarbamates, obtained in situ by reacting aryl carboxylic acids with hydroxycarbamates. The reaction offers facile access to structurally diverse arylamines with the site-specific formation of the C(sp2)-N bond under mild conditions.

Zinc chloride promoted efficient and facile BOC protection of amines

Amines are efficiently protected as their BOC derivatives under mild reaction conditions when reacted with BOC anhydride in presence of ZnCl2. The present method is applicable to a variety of amines including aliphatic, aromatic as well as heteroaromatic amines. This protocol appears to be competitive and in some cases superior to previously reported procedures that work under basic conditions.