35446-84-5Relevant articles and documents
Synthesis of β-hydroxy aryl selenides via transition-metal-free three-component reaction of arylamines, elemental selenium, and epoxides
Wang, Hongwei,Li, Hongchen,Bai, Yalong,Hei, Yanling,Chen, Junwei,Yu, Guoqi,Zhou, Yun-Bing
supporting information, p. 3621 - 3629 (2021/06/21)
An efficient protocol for the construction of valuable β-hydroxy aryl selenides from easily available arylamines, elemental selenium, and epoxides through a transition-metal-free radical process is described. A wide variety of β-hydroxy aryl selenides were obtained in good to excellent yields with excellent stereo- and regioselectivity. In this reaction, two C-Se bonds can be built along with the cleavage of a C-N and C-O bond, demonstrating the high step economy and efficiency of this approach.
New Catalytic Method for the Synthesis of β-Hydroxy Selenides
Zhang, Yikun,Wu, Sixue,Yan, Jie
, p. 654 - 658 (2016/08/24)
In the presence of NH4I as catalyst and m-chloroperbenzoic acid as oxidant, the Se–Se bond cleavage of diselenides undergoes smoothly. The in?situ generated reactive electrophilic Se species reacts with alkenes quickly, and a series of β-hydroxy selenides are prepared in good yields. This new catalytic method for synthesis of β-hydroxy selenides is a stereospecific anti addition, which occurs with a Markovnikov orientation.
A simple zinc-mediated preparation of selenols
Santi, Claudio,Santoro, Stefano,Testaferri, Lorenzo,Marcello Tiecco
scheme or table, p. 1471 - 1474 (2009/04/07)
Under acidic conditions zinc reduces diselenides to afford selenols, which can be either isolated or treated in situ with alkyl halides to produce alkyl selenides or with epoxides to give β-hydroxyselenides. Georg Thieme Verlag Stuttgart.
