3545-84-4 Usage
General Description
The chemical (2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl trihydrogen diphosphate is a compound with a complex structure and a range of potential biological functions. It contains a 1,4,7,8-tetrahydropteridin ring and a trihydrogen diphosphate group. (2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl trihydrogen diphosphate is likely involved in biochemical processes related to pteridine metabolism and folate synthesis, given its pteridinylmethyl structure. Pteridines are essential for a variety of biological processes, including the production of tetrahydrobiopterin, a cofactor for various enzymes involved in neurotransmitter synthesis and nitric oxide production. Additionally, diphosphate groups are important in cellular energy metabolism and the synthesis of DNA and RNA. Further analysis and research are needed to fully understand the specific roles and potential applications of (2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl trihydrogen diphosphate in biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 3545-84-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,5,4 and 5 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 3545-84:
(6*3)+(5*5)+(4*4)+(3*5)+(2*8)+(1*4)=94
94 % 10 = 4
So 3545-84-4 is a valid CAS Registry Number.
3545-84-4Relevant articles and documents
Comparative genomics guided discovery of two missing archaeal enzyme families involved in the biosynthesis of the pterin moiety of tetrahydromethanopterin and tetrahydrofolate
De Crecy-Lagard, Valerie,Phillips, Gabriela,Grochowski, Laura L.,Yacoubi, Basma El,Jenney, Francis,Adams, Michael W. W.,Murzin, Alexey G.,White, Robert H.
, p. 1807 - 1816 (2012)
C-1 carriers are essential cofactors in all domains of life, and in Archaea, these can be derivatives of tetrahydromethanopterin (H4-MPT) or tetrahydrofolate (H4-folate). Their synthesis requires 6-hydroxymethyl-7,8-dihydropterin dip
Structure-based design and development of functionalized mercaptoguanine derivatives as inhibitors of the folate biosynthesis pathway enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from staphylococcus aureus
Dennis, Matthew L.,Chhabra, Sandeep,Wang, Zhong-Chang,Debono, Aaron,Dolezal, Olan,Newman, Janet,Pitcher, Noel P.,Rahmani, Raphael,Cleary, Ben,Barlow, Nicholas,Hattarki, Meghan,Graham, Bim,Peat, Thomas S.,Baell, Jonathan B.,Swarbrick, James D.
, p. 9612 - 9626 (2015/02/02)
6-Hydroxymethyl-7,8-dihydropterin pyrophosphokinase (HPPK), an enzyme from the folate biosynthesis pathway, catalyzes the pyrophosphoryl transfer from ATP to 6-hydroxymethyl-7,8-dihydropterin and is a yet-to-be-drugged antimicrobial target. Building on ou
