35453-46-4

Basic information

• Product Name: Benzoic acid, 3-(2,2,2-trifluoroethoxy)-, methyl ester
• CAS NO: 35453-46-4
• Molecular Formula: C10H9F3O3
• Molecular Weight: 234.175
• Mol File: 35453-46-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 3-(2,2,2-trifluoroethoxy)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3-(2,2,2-trifluoroethoxy)-, methyl ester(35453-46-4)
• EPA Substance Registry System: Benzoic acid, 3-(2,2,2-trifluoroethoxy)-, methyl ester(35453-46-4)

Safety Data

• Hazardous Substances Data: 35453-46-4(Hazardous Substances Data)

Upstream product

• 25236-64-0 2,2,2-trifluoroethyl methanesulfonate 
• 19438-10-9 methyl 3-hydroxybenzoate 
• 13036-02-7 Dimethyl 5-hydroxyisophthalate 
• 75-89-8 2,2,2-trifluoroethanol 
• 99769-19-4 [3-(methoxycarbonyl)phenyl]boronic acid 

Downstream Products

• 35480-48-9 3-(2,2,2-trifluoroethoxy)benzoic acid 

Relevant articles and documents

Facile synthesis of trifluoroethyl aryl ethers through copper-catalyzed coupling of CF3CH2OH with aryl- and heteroaryl boronic acids

An efficient copper-catalyzed Chan-Lam reaction of trifluoroethanol with a variety of aryl- and heteroaryl boronic acids has been developed. This research provides a practical method to synthesize trifluoroethyl aryl ethers in moderate to good yields under mild conditions.