354548-73-5 Usage
General Description
3-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid is a chemical compound with the molecular formula C7H4BrN3O2. It is a heterocyclic organic compound that contains a pyridine ring fused to an imidazole ring with a carboxylic acid group attached at the 2-position. 3-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. It has been found to have potential biological activities and is being studied for its potential use in drug development. Additionally, 3-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid has shown promise as a tool compound for the study of various biochemical processes due to its unique structure and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 354548-73-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,4,5,4 and 8 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 354548-73:
(8*3)+(7*5)+(6*4)+(5*5)+(4*4)+(3*8)+(2*7)+(1*3)=165
165 % 10 = 5
So 354548-73-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H5BrN2O2/c9-7-6(8(12)13)10-5-3-1-2-4-11(5)7/h1-4H,(H,12,13)
354548-73-5Relevant articles and documents
Identification of fused bicyclic heterocycles as potent and selective 5-HT2A receptor antagonists for the treatment of insomnia
Xiong, Yifeng,Ullman, Brett,Choi, Jin-Sun Karoline,Cherrier, Martin,Strah-Pleynet, Sonja,Decaire, Marc,Feichtinger, Konrad,Frazer, John M.,Yoon, Woo H.,Whelan, Kevin,Sanabria, Erin K.,Grottick, Andrew J.,Al-Shamma, Hussien,Semple, Graeme
scheme or table, p. 1870 - 1873 (2012/04/17)
A series of fused bicyclic heterocycles was identified as potent and selective 5-HT2A receptor antagonists. Optimization of the series resulted in compounds that had improved PK properties, favorable CNS partitioning, good pharmacokinetic properties, and significant improvements on deep sleep (delta power) and sleep consolidation.