354574-31-5

Basic information

• Product Name: BENZENAMINE, 2-IODO-6-METHOXY-
• Synonyms: BENZENAMINE, 2-IODO-6-METHOXY-;2-Amino-3-iodoanisole, 6-Iodo-o-anisidine;2-Iodo-6-methoxyaniline
• CAS NO: 354574-31-5
• Molecular Formula: C₇H₈INO
• Molecular Weight: 249.046
• Mol File: 354574-31-5.mol

Chemical Properties

• Boiling Point: 291.0±25.0 °C(Predicted)
• Appearance: /
• Density: 1.807±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.48±0.10(Predicted)
• CAS DataBase Reference: BENZENAMINE, 2-IODO-6-METHOXY-(CAS DataBase Reference)
• NIST Chemistry Reference: BENZENAMINE, 2-IODO-6-METHOXY-(354574-31-5)
• EPA Substance Registry System: BENZENAMINE, 2-IODO-6-METHOXY-(354574-31-5)

Safety Data

• Hazardous Substances Data: 354574-31-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Benzenamine, 2-iodo-6-methoxy-, is used as a key building block in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, Benzenamine, 2-iodo-6-methoxy-, serves as a precursor in the preparation of agrochemicals, contributing to the development of effective pesticides and other agricultural products.
Used in Dye Industry:
Benzenamine, 2-iodo-6-methoxy-, is utilized as a starting material in the production of dyes, thanks to its reactivity and ability to form a variety of colored compounds.
Used in Organic Synthesis:
As a versatile chemical compound, Benzenamine, 2-iodo-6-methoxy-, is employed in organic synthesis for the preparation of a wide range of useful products, including intermediates for further chemical reactions and specialty chemicals.

Upstream product

• 154150-18-2 tert-butyl 2-methoxyphenylcarbamate 
• 90-04-0 2-methoxy-phenylamine 
• 194869-15-3 2-(N-tert-butoxycarbonylamino)-1-iodo-3-methoxybenzene 

Downstream Products

• 1609244-18-9 C₁₉H₁₉NO₂ 
• 1369922-18-8 2-iodo-6-methoxy-N,N-dimethylaniline 
• 1374687-55-4 C₂₂H₂₀N₂O₄S 
• 1354311-00-4 C₁₆H₁₄INO₂ 
• 838828-56-1 (2E)-N-(2-iodo-6-methoxyphenyl)-5-amino-2-methyl-5-phenyl-2-penten-1-ol acetate 
• 838828-48-1 (2E)-N-(2-iodo-6-methoxyphenyl)-5-amino-2-methyl-5-phenylpent-2-en-1-nal 
• 655240-18-9 (1S,3R)-2-Benzyl-8-methoxy-1-(2-methoxycarbonyl-ethyl)-9-methyl-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic acid ethyl ester 
• 655240-19-0 C₂₃H₂₄N₂O₂ 
• 655240-17-8 2-benzylamino-3-(7-methoxy-1-methyl-1H-indol-3-yl)-propionic acid ethyl ester 
• 655239-35-3 N_a-methyl-7-methoxy-D-tryptophan ethyl ester 
• 655240-16-7 7-methoxy-D-tryptophan ethyl ester 
• 25198-03-2 L-7-methoxytryptophan 
• 949115-25-7 tert-butyl (1,4-dioxaspiro[4.5]dec-7-en-8-ylacetyl)(2-iodo-6-methoxyphenyl)carbamate 
• 478849-86-4 2-(1,4-dioxaspiro[4.5]dec-7-en-8-yl)-N-(2-iodophenyl)-N-methylacetamide 

Relevant articles and documents

The cooperative FeCl3/DDQ system for the regioselective synthesis of 3-arylindoles from β-monosubstituted 2-alkenylanilines

A highly regioselective synthesis of 3-arylindoles by using the cooperative FeCl3/DDQ system has been developed. This new protocol represents an attractive route for the synthesis of 3-arylindoles from readily accessible non-indole precursors, β-aryl-substituted 2-styrylanilines, using an inexpensive catalyst and oxidant. Noteworthy is the unique synergetic and synergistic effect of FeCl3 and DDQ on the 1,2-aryl migratory process.

Gold- and indium-catalyzed synthesis of 3- and 6-sulfonylindoles from ortho-alkynyl-N-sulfonylanilines

(Chemical Equation Presented) Consecutive formation of C-N and C-S bonds: The gold-catalyzed intramolecular aminosulfonylation of 2-alkynyl-N- sulfonylanilines 1 (R1 = H) produces 3-sulfonylindoles 2 in good to high yields, whereas the indium-c

Synthesis of ring-A-substituted tryptophan by a palladium-catalyzed heteroannulation reaction

Coupling of substituted o-iodoanilines with methyl (S)-2-N,N-di-tert- butoxycarbonyl-5-oxo-pentanoate, derived from glutamic acid, in DMF in the presence of palladium acetate and DABCO provides substituted tryptophans in good to excellent yields. Georg Thieme Verlag Stuttgart.