35498-29-4

Basic information

• Product Name: 2-methyl-N-(pyridin-2-yl)benzamide
• Synonyms: 2-methyl-N-(pyridin-2-yl)benzamide
• CAS NO: 35498-29-4
• Molecular Weight: 212.251
• Mol File: 35498-29-4.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 2-methyl-N-(pyridin-2-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-N-(pyridin-2-yl)benzamide(35498-29-4)
• EPA Substance Registry System: 2-methyl-N-(pyridin-2-yl)benzamide(35498-29-4)

Safety Data

• Hazardous Substances Data: 35498-29-4(Hazardous Substances Data)

Upstream product

• 109-09-1 2-chloropyridine 
• 527-85-5 o-Methylbenzamid 
• 504-29-0 2-aminopyridine 
• 577-16-2 2-Methylacetophenone 
• 7287-82-3 1-O-tolyl-ethanol 
• 611-14-3 2-Ethyltoluene 
• 51012-65-8 2-bromo-1-o-tolylethanone 
• 766-47-2 1-ethynyl-2-methylbenzene 
• 118-90-1 ortho-methylbenzoic acid 

Downstream Products

• 1264292-85-4 N,2-dimethyl-N-(pyridin-2-yl)benzamide 

Relevant articles and documents

Cu-catalyzed cross-coupling of methyl ketones and pyridin-2-amines for the synthesis of N-(2-pyridyl)-α-ketoamides

An efficient copper-catalyzed strategy for the synthesis of α-ketoamides via cross-coupling of methyl ketones and pyridin-2-amines is described. This transformation has provided a simple process for the formation of C?N and C=O bonds to prepare α-ketoamid

Direct Transformation of Alkylarenes into N-(Pyridine-2-yl)amides by C(sp3)–C(sp3) Bond Cleavage

C(sp3)–H bond functionalization and C(sp3)–C(sp3) bond cleavage are very challenging transformations in chemistry. Herein, we report a mild and green methodology for the construction of N-(pyridine-2-yl)amides via tandem C(sp3)–H activation/C–C bond cleavage of alkylarenes. Various N-heterocyclic amides were directly synthesized from alkylarenes in water in moderate to good yields.

Diverse Oxidative C(sp2)-N Bond Cleavages of Aromatic Fused Imidazoles for Synthesis of α-Ketoamides and N-(pyridin-2-yl)arylamides

An efficient and chemoselective C(sp2)-N bond cleavage of aromatic imidazo[1,2-a]pyridine molecules is developed. A broad scope of amide compounds such as α-ketoamides and N-(pyridin-2-yl)arylamides are afforded as the final products in up to quantitative yields. Diverse C-N bond cleavages are controlled by the oxidative species used in this transformation, with various amide products afforded in a chemoselective fashion. A preliminary study indicated that some α-ketoamides exhibit anti-Tobacco Mosaic Virus activity for potential use in plant protection.