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β-dimethylamino-N-phenylpropionic acid amide, also known as prolintane, is a synthetic stimulant drug that belongs to the phenylpropanolamine class. It is structurally similar to ephedrine and amphetamine, and has been used as a central nervous system stimulant for the treatment of conditions such as narcolepsy and attention deficit hyperactivity disorder (ADHD). However, due to its potential for abuse and side effects, its use has been restricted or discontinued in many countries. The chemical is known for its sympathomimetic effects, which can include increased heart rate, blood pressure, and alertness, but also carries risks such as addiction and cardiovascular issues.

35508-99-7

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35508-99-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 35508-99-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,5,0 and 8 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 35508-99:
(7*3)+(6*5)+(5*5)+(4*0)+(3*8)+(2*9)+(1*9)=127
127 % 10 = 7
So 35508-99-7 is a valid CAS Registry Number.

35508-99-7Relevant academic research and scientific papers

LiCl-promoted amination of β-methoxy amides (γ-lactones)

Jia, Wen-Qiang,Pan, Xian-Dao,Shen, Long-Ying,Wang, Xiao-Jian,Zeng, Bing-Lin,Zhao, Hong-Yi,Zhao, Ru

, p. 34938 - 34942 (2020/10/14)

An efficient and mild method has been developed for the amination of β-methoxy amides (γ-lactones) including natural products michelolide, costunolide and parthenolide derivatives by using lithium chloride in good yields. This reaction is applicable to a wide range of substrates with good functional group tolerance. Mechanism studies show that the reactions undergo a LiCl promoted MeOH elimination from the substrates to form the corresponding α,β-unsaturated intermediates followed by the Michael addition of amines.

MANUFACTURING METHOD OF β-SUBSTITUTED PROPIONIC ACID AMIDE AND N-SUBSTITUTED (METH)ACRYLAMIDE

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Paragraph 0052; 0053; 0054, (2018/07/03)

PROBLEM TO BE SOLVED: To provide a method for industrially manufacturing β-alkoxy propionic acid amide, β-amino propionic acid amide and N-substituted (meth)acryl amide using (meth)acrylic acid ester as starting material at high yield and high purity. SOLUTION: There is provided a method for obtaining N-substituted (meth)acryl amide represented by target compound formula (7) by conducting an amidation reaction with amine using β-substituted propionic acid ester represented by the formula (1) of a product of a Michael addition reaction of (meth)acrylic acid ester and alcohol or amine in presence of a metal complex as a catalyst to obtain β-substituted propionic acid amide represented by the formula (3) and conducting a thermal decomposition reaction of β-substituted propionic acid amide in presence of the metal complex as the catalyst to eliminate alcohol or amine. A-CH2-C(R1)H-C(=O)-OR2 (1), A-CH2-C(R1)H-C(=O)-N(R3)R4 (3), CH2=C(R1)-C(=O)-N(R3)R4 (7) SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

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