35511-01-4

Basic information

• Product Name: 2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-N-phenyl-, 1,1-dioxide
• CAS NO: 35511-01-4
• Molecular Formula: C15H12N2O4S
• Molecular Weight: 316.337
• Mol File: 35511-01-4.mol

Chemical Properties

• CAS DataBase Reference: 2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-N-phenyl-, 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-N-phenyl-, 1,1-dioxide(35511-01-4)
• EPA Substance Registry System: 2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-N-phenyl-, 1,1-dioxide(35511-01-4)

Safety Data

• Hazardous Substances Data: 35511-01-4(Hazardous Substances Data)

Upstream product

• 35511-16-1 2-benzyl-1,1-dioxo-2,3-dihydro-1H-1λ⁶-benzo[e][1,2]thiazin-4-one 
• 35624-81-8 2-benzyl-2,3-dihydro-spiro[benzo[e][1,2]thiazine-4,2'-[1,3]dioxolane] 1,1-dioxide 
• 587-65-5 N-chloroacetyl-aniline 
• 128-44-9 saccharin sodium salt 
• 86048-59-1 2-(Phenylcarbamoylmethyl-sulfamoyl)-benzoic acid methyl ester 
• 15059-17-3 N-phenyl-2-(1,1,3-trioxo-1,3-dihydro-1λ⁶-benzo[d]isothiazol-2-yl)-acetamide 
• 124-41-4 sodium methylate 
• 35510-99-7 2-benzyl-1,1,4-trioxo-1,2,3,4-tetrahydro-1λ⁶-benzo[e][1,2]thiazine-3-carboxylic acid anilide 
• 24683-21-4 4-hydroxy-2H-1,2-benzothiazine-3-carboxylic acid ethyl ester 1,1-dioxide 
• 62-53-3 aniline 

Downstream Products

• 40713-36-8 2-cyanomethyl-1,1,4-trioxo-1,2,3,4-tetrahydro-1λ⁶-benzo[e][1,2]thiazine-3-carboxylic acid anilide 

Relevant articles and documents

Process for the preparation of 4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides

A novel process for preparing 4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides is disclosed. The process involves the base catalyzed rearrangement of a saccharinacetamide of structure I to give II, STR1 wherein R1 is hydrogen or lower alkyl and R2 is lower alkyl, aryl or a heterocyclic ring selected from the group consisting of pyridyl, substituted-pyridyl, and thiazolyl. Compounds of the formula II have useful anti-inflammatory properties. In addition, they can be used as intermediate in the preparation of known anti-inflammatory agents.