3560-45-0Relevant academic research and scientific papers
Synthesis of 12-membered macrocyclic templates and library analogs for PPI
Chen, Jinshan,Rong, Frank,Shan, Bo,Chen, Yuanwei,Li, Yingfu,Yu, Hua,Chen, Li,Kuang, Tongtao,Li, Shai,Chen, Youpei,Du, Jing,Ai, Chaowu,Li, Jian,Li, Xiaoyong,Shi, Changqing,Jiang, Zhilong,Long, Yuanqiang,Gao, Qiu,Wang, Zhibo,Xu, Kexin,Ran, Xin,Yi, Hua,Zhao, Dapeng,Qiao, Hongyun,Shen, Junwei,Liu, Bo,Liu, Chonggang,Wu, Kai,Geng, Xi,Tan, Jieyang,McLeod, Dale,Frost, Heather,Bai, Guoyun,Goetz, Gilles,Federico III, James,Whitney-Pickett, Carrie,Troutman, Matthew,Noe, Mark C.,Guimaraes, Cristiano,Piotrowski, David W.,Magee, Thomas V.
, p. 3298 - 3301 (2013)
We report novel syntheses of 12-membered macrocyclic templates and a library of 4000 macrocyclic analogs. The key macrocyclization step was performed at up to 100 g scale without resorting to syringe pumps, flow reactors or large volumes of solvent. An in
Preparation method N - (2 - aminoethyl) glycine derivative
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Paragraph 0019; 0080; 0084-0086; 0089-0091; 0094-0096, (2021/10/16)
The N - (2 - aminoethyl) glycine derivative product compound is obtained by taking hydroxyethyl ethylenediamine as a raw material, Cbz protecting the primary amine and then oxidizing the reaction, and N - (2 - aminoethyl) glycine derivative. To the prepar
ANTIBACTERIAL AMIDE MACROCYCLES VI
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Page/Page column 32, (2008/06/13)
The invention concerns antibacterial amide macrocycles , methods for producing same, their use for treating and/or preventing diseases, as well as their use for producing drugs for treating and/or preventing diseases, in particular bacterial infections.
