3563-36-8 Usage
Uses
Used in Pharmaceutical Industry:
1,2-BIS(2-CHLOROETHYL(THIO)ETHANE is used as a chemotherapeutic agent for its alkylating properties, which can form cross-links with DNA, leading to the disruption of cellular replication and ultimately causing cell death. This makes it a potent compound in the treatment of various types of cancer.
Used in Research and Development:
In the field of research and development, 1,2-BIS(2-CHLOROETHYL(THIO)ETHANE is utilized as a starting material or intermediate in the synthesis of other alkylating agents and related compounds with potential applications in cancer therapy and other medical treatments.
Used in Chemical Synthesis:
1,2-BIS(2-CHLOROETHYL(THIO)ETHANE can be used as a reagent in chemical synthesis processes, particularly in the production of other pharmaceutical compounds and organic molecules that may have various applications in different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 3563-36-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,5,6 and 3 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3563-36:
(6*3)+(5*5)+(4*6)+(3*3)+(2*3)+(1*6)=88
88 % 10 = 8
So 3563-36-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H12Cl2S2/c7-1-3-9-5-6-10-4-2-8/h1-6H2
3563-36-8Relevant academic research and scientific papers
Thermal degradation of bis (2-chloroethyl) sulfide (mustard gas)
Wagner, George W.,Maciver, Brian K.,Rohrbaugh, Dennis K.,Yang, Yu-Chu
, p. 65 - 76 (2007/10/03)
The thermal degradation of mustard gas (ClCH2CH2SCH2CH2Cl, HD ), with and without 5% added water, is examined. GC/MS, LC/MS and NMR were employed to comprehensively analyze the products. After 75 days at 90°C, 91% HD remains (80% with 5% water). After 40 days at 140°C, 30% HD remains (24% with 5% water) and black tar precipitates form. The apparent Ea is 22.4 kcal/mol. Major products include Q (ClCH2CH2SCH2CH2SCH2CH2Cl), 1,2-dichloroethane, polysulfides and 1,4-dithiane. With 5% water, oxygenates such as 1,4-thioxane and 2-chloroethanol are produced as are numerous sulfonium ions, including S-(2-chlorethyl)-1,4-dithianium, a major component of mustard heels. The decomposition does not go to completion due to the equilibrium nature of the reaction at these temperatures.
