356560-90-2

Usage

Uses

Used in Pharmaceutical Development:
2-(6-Methylpyridin-2-yl)-1-(quinoxalin-6-yl)ethanone is used as a building block or intermediate in the synthesis of pharmaceuticals due to its distinctive structure and functional groups. It may contribute to the development of new drugs with specific therapeutic properties.
Used in Agrochemical Production:
In the agrochemical industry, 2-(6-Methylpyridin-2-yl)-1-(quinoxalin-6-yl)ethanone is used as a key component in the creation of novel agrochemicals. Its chemical properties could be harnessed to develop pesticides or herbicides with improved efficacy and selectivity.
Used in Material Science:
2-(6-Methylpyridin-2-yl)-1-(quinoxalin-6-yl)ethanone is utilized as a component in the development of advanced materials. Its incorporation into material formulations could lead to new properties, such as enhanced stability or reactivity, depending on the application.
Further research and testing are required to fully explore the properties and potential uses of 2-(6-Methylpyridin-2-yl)-1-(quinoxalin-6-yl)ethanone, ensuring its safe and effective application across different industries.

Upstream product

• 108-48-5 2,6-dimethylpyridine 
• 258503-93-4 quinoxaline-6-carbonyl chloride 

Downstream Products

• 364050-21-5 1-(6-methylpyridin-2-yl)-2-(quinoxalin-6-yl)ethane-1,2-dione 
• 868612-83-3 IN-1130 
• 868612-72-0 4-((1-hydroxy-5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl)methyl)benzonitrile 
• 442517-38-6 2-(dimethoxymethyl)-5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazole 

Relevant academic research and scientific papers

Synthesis and biological evaluation of benzenesulfonamide-substituted 4-(6-alkylpyridin-2-yl)-5-(quinoxalin-6-yl)imidazoles as transforming growth factor-β type 1 receptor kinase inhibitors

A series of benzenesulfonamide-substituted 4-(6-alkylpyridin-2-yl)-5-(quinoxalin-6-yl)imidazoles (15a-l) have been synthesized and evaluated for their ALK5 inhibitory activity in cell-based luciferase reporter assays. Among them, 4-[5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-ylmethyl]b enzenesulfonamide (15b) and 4-[5-(6-ethylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-ylmethyl]be nzenesulfonamide (15c) showed more than 90% inhibition at 0.5 μM in a luciferase reporter assay using HaCaT cells transiently transfected with p3TP-luc reporter construct, but inhibited p38α MAP kinase activity only 11 and 8% at a concentration of 10 μM, respectively.

Synthesis and biological evaluation of 5-(pyridin-2-yl)thiazoles as transforming growth factor-β type1 receptor kinase inhibitors

A series of 5-(pyridin-2-yl)thiazoles (14a-l and 15a-l) has been synthesized and evaluated for their ALK5 inhibitory activity in cell-based luciferase reporter assays. Among them, 3-[[5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)thiazol-2-ylamino]methyl ]b

Synthesis and biological evaluation of 4(5)-(6-alkylpyridin-2-yl)imidazoles as transforming growth factor-β type 1 receptor kinase inhibitors

A series of 4(5)-(6-alkylpyridin-2-yl)imidazoles 13a-p, 17a, and 17b have been synthesized and evaluated for ALK5 inhibitory activity in an enzyme assay and in cell-based luciferase reporter assays. The quinoxalinyl analogue 13e inhibited ALK5 phosphoryla

Triarylimidazole derivatives as cytokine inhibitors

Compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2 and R3 are various substituent groups; and one of X1 and X2 is N or CR″, and the other is NR″ or CHR″ wherein R″