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Tert-butyl (4-nitrobenzoyl)oxycarbamate is a versatile chemical compound used in organic synthesis and research. It is characterized by the presence of a tert-butyl group, a 4-nitrobenzoyl group, and an oxycarbamate group, which contribute to its stability and reactivity. Known for its ability to protect amino groups in peptides and control the release of active ingredients in drug delivery systems, tert-Butyl (4-nitrobenzoyl)oxycarbaMate holds potential applications in the pharmaceutical and biotechnology industries.

35657-41-1

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35657-41-1 Usage

Uses

Used in Organic Synthesis:
Tert-butyl (4-nitrobenzoyl)oxycarbamate is used as a reagent in organic synthesis for its ability to protect amino groups in peptides. This protection allows for the selective modification of other functional groups in the peptide without affecting the amino groups, facilitating the synthesis of complex peptide structures.
Used in Drug Delivery Systems:
In the pharmaceutical industry, tert-butyl (4-nitrobenzoyl)oxycarbamate is used as a component in drug delivery systems to control the release of active ingredients. Its ability to protect amino groups enables the development of targeted drug delivery systems that can release the active ingredients at specific sites or under specific conditions, improving the efficacy and safety of the treatment.
Used in Research:
Tert-butyl (4-nitrobenzoyl)oxycarbamate is also utilized in research settings for the study of peptide chemistry and the development of new synthetic methods. Its unique properties make it a valuable tool for exploring the reactivity and stability of various chemical groups in peptides and other biomolecules.

Check Digit Verification of cas no

The CAS Registry Mumber 35657-41-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,6,5 and 7 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 35657-41:
(7*3)+(6*5)+(5*6)+(4*5)+(3*7)+(2*4)+(1*1)=131
131 % 10 = 1
So 35657-41-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H14N2O6/c1-12(2,3)19-11(16)13-20-10(15)8-4-6-9(7-5-8)14(17)18/h4-7H,1-3H3,(H,13,16)

35657-41-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name [(2-methylpropan-2-yl)oxycarbonylamino] 4-nitrobenzoate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:35657-41-1 SDS

35657-41-1Relevant academic research and scientific papers

Palladium-Catalyzed Decarboxylative Synthesis of Arylamines

Dai, Qipu,Li, Peihe,Ma, Nuannuan,Hu, Changwen

supporting information, p. 5560 - 5563 (2016/11/17)

A novel approach has been developed for the synthesis of arylamines via the palladium-catalyzed intramolecular decarboxylative coupling (IDC) of aroyloxycarbamates, obtained in situ by reacting aryl carboxylic acids with hydroxycarbamates. The reaction offers facile access to structurally diverse arylamines with the site-specific formation of the C(sp2)-N bond under mild conditions.

[1,2,4]TRIAZOLOPYRIDINES AND THEIR USE AS PHOSPODIESTERASE INHIBITORS

-

, (2013/07/05)

The present invention relates to novel [1,2,4]triazolopyridine compounds with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.

Fischer synthesis of isomeric thienopyrrole LHRH antagonists

Andrews, David M.,Arnould, Jean-Claude,Boutron, Pascal,Délouvrie, Bénédicte,Delvare, Christian,Foote, Kevin M.,Hamon, Annie,Harris, Craig S.,Lambert-van der Brempt, Christine,Lamorlette, Maryannick,Matusiak, Zbegniew M.

experimental part, p. 5805 - 5816 (2009/12/24)

As part of a structure-activity exploration into LHRH antagonists, structures containing the thieno[2,3-b]pyrrole core were identified as potent antagonists. This letter describes the employment of the Fischer synthesis to access this thienopyrrole and isomeric final compounds.

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