356759-65-4Relevant academic research and scientific papers
Design, synthesis, DNA binding, and biological evaluation of water-soluble hybrid molecules containing two pyrazole analogues of the alkylating cyclopropylpyrroloindole (CPI) subunit of the antitumor agent CC-1065 and polypyrrole minor groove binders
Baraldi,Balboni,Pavani,Spalluto,Tabrizi,De Clercq,Balzarini,Bando,Sugiyama,Romagnoli
, p. 2536 - 2543 (2001)
We have synthesized and evaluated a series of hybrids, denoted 22-27, for in vitro cytotoxic activity against a variety of cancer cell lines. These hybrids represent a molecular combination of polypyrrole minor groove binders structurally related to the n
