357193-14-7

Basic information

• Product Name: 5-[2-(7-azabicyclo[2.2.1]hept-7-yl)-1,1-dimethyl-2-oxoethyl]-3-[(1S)-2-(benzyloxy)-1-methylethyl]-2-(3,4,5-trimethylphenyl)-1H-indole
• Synonyms: 5-[2-(7-azabicyclo[2.2.1]hept-7-yl)-1,1-dimethyl-2-oxoethyl]-3-[(1S)-2-(benzyloxy)-1-methylethyl]-2-(3,4,5-trimethylphenyl)-1H-indole
• CAS NO: 357193-14-7
• Molecular Weight: 548.769
• Mol File: 357193-14-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[2-(7-azabicyclo[2.2.1]hept-7-yl)-1,1-dimethyl-2-oxoethyl]-3-[(1S)-2-(benzyloxy)-1-methylethyl]-2-(3,4,5-trimethylphenyl)-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[2-(7-azabicyclo[2.2.1]hept-7-yl)-1,1-dimethyl-2-oxoethyl]-3-[(1S)-2-(benzyloxy)-1-methylethyl]-2-(3,4,5-trimethylphenyl)-1H-indole(357193-14-7)
• EPA Substance Registry System: 5-[2-(7-azabicyclo[2.2.1]hept-7-yl)-1,1-dimethyl-2-oxoethyl]-3-[(1S)-2-(benzyloxy)-1-methylethyl]-2-(3,4,5-trimethylphenyl)-1H-indole(357193-14-7)

Safety Data

• Hazardous Substances Data: 357193-14-7(Hazardous Substances Data)

Upstream product

• 357193-25-0 5-[2-(7-azabicyclo[2.2.1]hept-7-yl)-1,1-dimethyl-2-oxoethyl]-3-[(1S)-2-(benzyloxy)-1-methylethyl]-2-(triethylsilyl)-1H-indole 
• 357192-99-5 4-[2-(7-azabicyclo[2.2.1]hept-7-yl)-1,1-dimethyl-2-oxoethyl]-2-iodoaniline 
• 246219-83-0 (S)-(4-benzyloxy-3-methylbut-1-ynyl)triethylsilane 
• 357193-08-9 2-(4-amino-phenyl)-1-(7-aza-bicyclo[2.2.1]hept-7-yl)-2-methyl-propan-1-one 
• 246219-82-9 (S)-(((4,4-dibromo-2-methylbut-3-en-1-yl)oxy)methyl)benzene 
• 357193-27-2 trifluoromethanesulfonic acid 3,4,5-trimethylphenyl ester 
• 56850-58-9 methyl (2R)-3-(benzyloxy)-2-methylpropanoate 
• 79026-61-2 (R)-3-benzyloxy-2-methylpropanal 
• 42206-47-3 2-methyl-2-(4-nitro-phenyl)-propionic acid 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 63930-46-1 (S)-3-benzyloxy-2-methylpropan-1-ol 
• 83397-45-9 ethyl 2-methyl-2-(4-nitrophenyl)propanoate 
• 357193-13-6 4,4,5,5-tetramethyl-2-(3,4,5-trimethylphenyl)[1,3,2]dioxaborolane 
• 357193-12-5 5-[2-(7-azabicyclo[2.2.1]hept-7-yl)-1,1-dimethyl-2-oxoethyl]-3-[(1S)-2-(benzyloxy)-1-methylethyl]-2-iodo-1H-indole 

Downstream Products

• 357193-16-9 tert-butyl 5-[2-(7-azabicyclo[2.2.1]hept-7-yl)-1,1-dimethyl-2-oxoethyl]-3-[(1S)-2-hydroxy-1-methylethyl]-2-(3,4,5-trimethylphenyl)-1H-indole-1-carboxylate 
• 357193-19-2 tert-butyl 5-[2-(7-azabicyclo[2.2.1]hept-7-yl)-1,1-dimethyl-2-oxoethyl]-3-[(1S)-2-amino-1-methylethyl]-2-(3,4,5-trimethylphenyl)-1H-indole-1-carboxylate 
• 357193-17-0 tert-butyl 5-[2-(7-azabicyclo[2.2.1]hept-7-yl)-1,1-dimethyl-2-oxoethyl]-3-[(1S)-2-azido-1-methylethyl]-2-(3,4,5-trimethylphenyl)-1H-indole-1-carboxylate 
• 357193-23-8 tert-butyl 5-[2-(7-azabicyclo[2.2.1]hept-7-yl)-1,1-dimethyl-2-oxoethyl]-3-[(1S)-1-methyl-2-[(2-pyridin-4-ylethyl)amino]ethyl]-2-(3,4,5-trimethylphenyl)-1H-indole-1-carboxylate 
• 357193-21-6 tert-butyl 5-[2-(7-azabicyclo[2.2.1]hept-7-yl)-1,1-dimethyl-2-oxoethyl]-3-[(1S)-2-{[(2,4-dinitrophenyl)sulfonyl]amino}-1-methylethyl]-2-(3,4,5-trimethylphenyl)-1H-indole-1-carboxylate 
• 357193-15-8 tert-butyl 5-[2-(7-azabicyclo[2.2.1]hept-7-yl)-1,1-dimethyl-2-oxoethyl]-3-[(1S)-2-(benzyloxy)-1-methylethyl]-2-(3,4,5-trimethylphenyl)-1H-indole-1-carboxylate 

Relevant articles and documents

A convergent synthesis of (S)-β-methyl-2-aryltryptamine based gonadotropin releasing hormone antagonists

A practical synthesis of (S)-β-methyl-2-aryltryptamine based gonadotropin releasing hormone antagonists which features a palladium-catalyzed Larock indole synthesis and a palladium-catalyzed Suzuki-Miyaura sequence to install the 2-position aryl substitue